Biology of Blood and Marrow Transplantation

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Stephanie J. Lee, Loretta A. Williams

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Presentation transcript:

Biology of Blood and Marrow Transplantation Cytomegalovirus Antigenic Mimicry of Human Alloreactive Peptides: Exploring Cross- Reactivity As a Potential Trigger for Graft Versus Host Disease Charles E. Hall, Vishal N. Koparde, Maximilian Jameson-Lee, Abdelrhman Elnasseh, Allison F. Scalora, David J. Kobulnicky, Myrna G. Serrano, Catherine H. Roberts, John M. McCarty, Harold M. Chung, William B. Clark, Christina M. Wiedl, Gregory A. Buck, Michael C. Neale, Daniel E. Nixon, Amir A. Toor Biology of Blood and Marrow Transplantation Volume 23, Issue 3, (March 2017) DOI: 10.1016/j.bbmt.2016.12.649 Copyright © 2016 Terms and Conditions

Figure 1 Bioinformatic pipeline comparing alloreactive peptide libraries with the CMV proteome for determination of potential Pro-GVHD DRP cross reactivity upon CMV reactivation correlated with GVHD-tissue specific distribution of peptides. Biology of Blood and Marrow Transplantation 2017 23, DOI: (10.1016/j.bbmt.2016.12.649) Copyright © 2016 Terms and Conditions