Quantitative analysis of continuous-wave Doppler spectral broadening for the diagnosis of carotid disease: Results of a multicenter study K.Wayne Johnston,

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Presentation transcript:

Quantitative analysis of continuous-wave Doppler spectral broadening for the diagnosis of carotid disease: Results of a multicenter study K.Wayne Johnston, M.D., William H. Baker, M.D., Steven J. Burnham, M.D., Andrew C. Hayes, P.A., Cynthia A. Kupper, R.N., RVT,, Mary Ann Poole, R.N., RVT Journal of Vascular Surgery Volume 4, Issue 5, Pages 493-504 (November 1986) DOI: 10.1016/0741-5214(86)90386-1 Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 1 Continuous-wave Doppler spectral recordings. A, Normal recording. B, Abnormal recording distal to stenosis shows spectral broadening. Note that quality of the gray scale information has been lost in the photographic reproduction. SBI = spectral broadening index; AVPK = average peak frequency. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 2 Three-dimensional plots of individual spectra that comprise one cardiac cycle and correspond to waveforms shown in Fig. 1. A, Normal. B, Abnormal. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 3 Doppler spectra at peak systole from waveforms shown in Figs. 1 and 2. A, Normal. B, Abnormal. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 4 Examples of plots of peak frequency and spectral broadening index (SBI) recorded from each of six recording sites. CC = common carotid artery; IC = internal carotid artery; EC = external carotid artery. A, Normal carotid artery. B, Internal carotid artery stenosis of 50%. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 5 Receiver operating characteristic curve for maximal peak frequency recorded from the internal carotid artery. Angiographic evidence of stenosis greater than 45% was considered a positive test. A 5 MHz probe has been used. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 6 Receiver operating characteristic curve for the maximal spectral broadening index recorded from the internal carotid artery. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 7 Population distributions for peak frequency and the fitted polynomial equations. A, Normal (i.e., less than 45% stenosis). B, Abnormal (i.e., greater than 45% stenosis). Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 8 For each value of peak frequency probability that individual patient has stenosis greater than 45% is plotted. A 5 MHz probe has been used. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 9 Population distributions for spectral broadening index (SBI) and the fitted polynomial equations. A, Normal (i.e., less than 45% stenosis). B, Abnormal (i.e., greater than 45% stenosis). Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 10 For each value of spectral broadening index (SBI), probability that individual patient has stenosis greater than 45% is plotted. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 11 Probability (%) that individual patient has carotid stenosis greater than 45% on basis of measurements of peak frequency and spectral broadening index. Contour lines are in 10% increments. A 5 MHz probe has been used. Journal of Vascular Surgery 1986 4, 493-504DOI: (10.1016/0741-5214(86)90386-1) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions