Distribution of splenic T cells, B cells, and NK cells in NSG hL-7xhIL-15 humanized mice. Distribution of splenic T cells, B cells, and NK cells in NSG.

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Distribution of splenic T cells, B cells, and NK cells in NSG hL-7xhIL-15 humanized mice. Distribution of splenic T cells, B cells, and NK cells in NSG hL-7xhIL-15 humanized mice. Thin sections of a hIL-7xhIL-15 NSG recipient spleen stained with anti-hCD56, anti-CD3 and anti-CD19 antibodies. Low and high magnification images are shown. hCD3+ T cell and hCD19+ B cells were found within lymphoid clusters, whereas CD56+ NK cells are located outside the clusters. Scale bars: low magnification, 50 μm; high magnification, 20 μm. Masashi Matsuda et al. LSA 2019;2:e201800195 © 2019 Matsuda et al.