Cardiac surgery with deep hypothermic circulatory arrest produces less systemic inflammatory response than low-flow cardiopulmonary bypass in newborns

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Presentation transcript:

Cardiac surgery with deep hypothermic circulatory arrest produces less systemic inflammatory response than low-flow cardiopulmonary bypass in newborns P. Tassani, MD, A. Barankay, MD, F. Haas, MD, S.U. Paek, MD, M. Heilmaier, J. Hess, MD, R. Lange, MD, J.A. Richter, MD The Journal of Thoracic and Cardiovascular Surgery Volume 123, Issue 4, Pages 648-654 (April 2002) DOI: 10.1067/mtc.2002.121285 Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 Concentration of C3a anaphylatoxin (in nanograms per milliliter). Control indicates the period after induction of anesthesia and before the operation. CPB indicates the period during CPB-rewarming, with a rectal temperature of 30°C. +0.5h, 0.5 hours after CPB; +2h, 2 hours after CPB; +4h, 4 hours after CPB; +24h, 24 hours after CPB. *Significant difference noted between the groups (P <.05, Mann-Whitney U test). The Journal of Thoracic and Cardiovascular Surgery 2002 123, 648-654DOI: (10.1067/mtc.2002.121285) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Concentration of interleukin 6 (in picograms per milliliter). Control indicates the period after induction of anesthesia and before the operation. CPB indicates the period during CPB-rewarming, with a rectal temperature of 30°C. +0.5h, 0.5 hours after CPB; +2h, 2 hours after CPB; +4h, 4 hours after CPB; +24h, 24 hours after CPB. *Significant difference noted between the groups (P <.05, Mann-Whitney U test). The Journal of Thoracic and Cardiovascular Surgery 2002 123, 648-654DOI: (10.1067/mtc.2002.121285) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 Concentration of interleukin 8 (in picograms per milliliter). Control indicates the period after induction of anesthesia and before the operation. CPB indicates the period during CPB-rewarming, with a rectal temperature of 30°C. +0.5h, 0.5 hours after CPB; +2h, 2 hours after CPB; +4h, 4 hours after CPB; +24h, 24 hours after CPB. *Significant difference noted between the groups (P <.05, Mann-Whitney U test). The Journal of Thoracic and Cardiovascular Surgery 2002 123, 648-654DOI: (10.1067/mtc.2002.121285) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 Weight gain (in grams): weight of the patient at the respective postoperative day minus the preoperative weight. The Journal of Thoracic and Cardiovascular Surgery 2002 123, 648-654DOI: (10.1067/mtc.2002.121285) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions