Leptin and inflammation-associated cachexia in chronic kidney disease

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Presentation transcript:

Leptin and inflammation-associated cachexia in chronic kidney disease R.H. Mak, W. Cheung, R.D. Cone, D.L. Marks Kidney International Volume 69, Issue 5, Pages 794-797 (March 2006) DOI: 10.1038/sj.ki.5000182 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Experimental strategies for treatment of uremic cachexia (Cheung et al.30). (1) Leptin receptor (OBRb) knockout. (2) MC-4R knockout. (3) AgRP, antagonist for MC-4R and MC-3R. Kidney International 2006 69, 794-797DOI: (10.1038/sj.ki.5000182) Copyright © 2006 International Society of Nephrology Terms and Conditions