Volume 139, Issue 2, Pages (August 2010)

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Volume 139, Issue 2, Pages 377-379 (August 2010) Inhibition of Transient Lower Esophageal Sphincter Relaxation in GERD: Will Lesogaberan Advance the Field? Gary W. Falk Gastroenterology Volume 139, Issue 2, Pages 377-379 (August 2010) DOI: 10.1053/j.gastro.2010.06.028 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Vagal pathways involved in TLESR. The sites where GABAB receptors are located are highlighted. LES, lower esophageal sphincter; DVN, dorsal vagal nuclei; NTS, nucleus tractus solitarius. Adapted from Blackshaw LA. Receptors and transmission in the brain-gut axis: potential for novel therapies. IV. GABA(B) receptors in the brain-gastroesophageal axis. Am J Physiol Gastrointest Liver Physiol 2001;281:G311–315. Used with permission of the American Physiology Society. Gastroenterology 2010 139, 377-379DOI: (10.1053/j.gastro.2010.06.028) Copyright © 2010 AGA Institute Terms and Conditions