Inflammatory response and CD34+CD45− cell release following percutaneous coronary intervention (PCI). Inflammatory response and CD34+CD45− cell release.

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Presentation transcript:

Inflammatory response and CD34+CD45− cell release following percutaneous coronary intervention (PCI). Inflammatory response and CD34+CD45− cell release following percutaneous coronary intervention (PCI). PCI rapidly but transiently mobilised CD34+CD45− cells into the peripheral circulation, peaking at 6 h; p=0.01. Circulating concentrations had fallen back to baseline by 24 h. In contrast, the systemic inflammatory response caused by PCI was relatively prolonged, with CRP concentrations continuing to increase for at least 48 h; p=0.001. Diagnostic coronary angiography alone did not cause an inflammatory response or effect the CD34+CD45− concentration; p>0.5 for all. Data are median and IQR. Gareth J Padfield et al. Open Heart 2014;1:e000047 ©2014 by British Cardiovascular Society