Time courses of SSc-PAH signatures.

Slides:

Advertisements

Similar presentations

Fibroblast activation in WT and NFATc2-deficient mice.

Advertisements

The adjMFC end point is independent of baseline titers.

Force limits and layout design.

Longitudinal analysis of cross-group HA stem–binding lineages.

Self-folding triangular devices at two scales.

Comparison of predicted and measured forces and moments.

Basic design concept of human mimetic humanoid.

TPAD controller schematic and testing for WPC.

TPAD controller performance for three force components.

Cable-driven system diagram for structure matrix.

Three different types of transfer functions with a codomain of [0,1].

TPAD training protocol.

Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells.

Longitudinal analysis of ZIKV E–specific memory B cell responses in the DENV-experienced donors. Longitudinal analysis of ZIKV E–specific memory B cell.

Assessment of repertoire elasticity and compartment replenishment after depletion. Assessment of repertoire elasticity and compartment replenishment after.

T2-weighted cross-sectional MR imaging of MSP swarms inside SD rats.

Protein sequence alignment of the NS3 helicase–encoding region of 63 flaviviruses demonstrates conservation of a KIR2DS2-binding peptide. Protein sequence.

Ex vivo testing of the soft robotic devices.

Human PBMC-derived MERS-CoV–specific T cells are multifunctional.

Group data during free walking between sessions 1 and 16.

Visual explanation of the interaction terms.

Visual explanation of the interaction terms.

Platelets are required for hFcγRIIA-induced anaphylaxis.

VH usage of cross-reactive B cells induced by H5N1 or H7N9 vaccination

Repertoire structure as relevant to vaccine response.

Comparison of repertoire distributions to baseline.

Dissection of oligoclonality.

Tukey boxplots overlaid on data points from objective and subjective measures, displaying results from study 1. Tukey boxplots overlaid on data points.

Study design and comparison of study groups across time.

Analysis of plasmablast responses in one naïve and three DENV-experienced donors. Analysis of plasmablast responses in one naïve and three DENV-experienced.

Protein sequence alignment of the NS3 helicase–encoding region of 63 flaviviruses demonstrates conservation of a KIR2DS2-binding peptide. Protein sequence.

Evidence for platelet activation during human drug-induced anaphylaxis

Online verification using reachable occupancies.

Illustration of the addressable wireless folding concept.

Antitumor effect of local cancer immunotherapy treatment in various tumor models. Antitumor effect of local cancer immunotherapy treatment in various tumor.

Force limits and layout design.

Baseline activity of the BCR signaling gene module (M54) is associated with influenza vaccination responses in young individuals. Baseline activity of.

Cell viability tests. Cell viability tests. SEM images of (A) MC3T3-E1 cells and (B) MSCs on days 1, 3, and 5 of culture. (C) Survival rates of MC3T3-E1.

Signatures of SSc-PAH compared with healthy Ig repertoires at baseline

Quantitative modeling of repertoire replenishment rates.

T2-weighted cross-sectional MR imaging of MSP swarms inside SD rats.

Fig. 7 Bacterial dependency networks in IgA deficiency and HDs.

The adjMFC end point is independent of baseline titers.

Fig. 2 Preserved long-term functionality of the TEHVs over 1-year follow-up as assessed by ICE and cardiac MRI flow measurements. Preserved long-term functionality.

Inverse correlation of baseline differences between young and older participants. Inverse correlation of baseline differences between young and older participants.

Evaluation of multidonor class Ig sequences obtained from H5N1 and H7N9 vaccinated donors. Evaluation of multidonor class Ig sequences obtained from H5N1.

Fig. 1 Map of water stress and shale plays.

Details of an implementation of a mechanism within the control chambers for selective lengthening of the sides of the soft robot. Details of an implementation.

Drug response profiles and experimental validation.

Comparison of predicted and measured forces and moments.

Tfr cells respond better to immunization with self-antigens than with foreign antigens. Tfr cells respond better to immunization with self-antigens than.

Results of a representative participant with multiple training sessions. Results of a representative participant with multiple training sessions. Average.

Fig. 2. Mutational signature exposures in Taiwan HCCs and summary of AA signature mutations. Mutational signature exposures in Taiwan HCCs and summary.

AEGIS autonomous targeting process.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 2 Results of the learning and testing phases.

Contrast agent uptake for the four different groups of MMA mice

Fig. 1 Gradients of species richness and predicted turnover through extinction and redistribution. Gradients of species richness and predicted turnover.

Fig. 2 Dynamics of Nef-stop repair and predictors of viral set-point.

Fig. 5. High burdens of AA signature mutations and predicted immunogenicity in Taiwan HCCs. High burdens of AA signature mutations and predicted immunogenicity.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Fibroblast activation in WT and NFATc2-deficient mice.

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 1 Example of diversified propagation patterns of the MJO.

Onboard sensors enable state feedback and closed-loop control of robotic skins. Onboard sensors enable state feedback and closed-loop control of robotic.

Cartoon model for the increased p-HLA display engendered by peptide splicing. Cartoon model for the increased p-HLA display engendered by peptide splicing.

Fig. 6 Net primary productivity after nuclear war.

In response to allergen, T cells and ILCs are equally important sources of IL-13. In response to allergen, T cells and ILCs are equally important sources.

Fig. 2 Imaging blood vessel before and after closure.

Fig. 2 Proportion of time the listener spent looking upward across original recording conditions of the playback stimuli. Proportion of time the listener.

Presentation transcript:

Time courses of SSc-PAH signatures. Time courses of SSc-PAH signatures. Dashed black lines indicate the range of values observed in healthy participants at baseline. Note that the data displayed for study arms A and B in the present figure (longitudinal experiment) were acquired in a separate batch from the data on healthy participants (cross-sectional experiment; already described in Fig. 2) and so may not be directly comparable to the healthy data; we nevertheless include the dashed lines as a guide. (A) IgD proportion. (B) IgD mutation loads. (C) Percentage of lineages using the IGHV2-5 segment (all isotypes combined). (D) Proportion of somatic mutations observed in a lineage that were considered “fixed,” that is, present in at least 80% of the lineage’s sequences. The proportion of fixed mutations was calculated separately for each lineage containing between 5 and 29 distinct sequences and then averaged across all those lineages. Charles F. A. de Bourcy et al. Sci. Immunol. 2017;2:eaan8289 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works