BioGRID: Biological General Repository for Interaction Datasets

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Presentation transcript:

BioGRID: Biological General Repository for Interaction Datasets Ben Bachman Georgia Institute of Technology 28 June, 2006

Overview Database of protein-protein interactions Removes redundancies Search protein of interest Retrieve primary information Physical and genetic interaction data Links to other databases http://www.thebiogrid.org

Features Overview Realtime site statistics Can search an organism by Genebank ID Entrez-Gene ID SGD ID Gene name Links to all known related enzymes Links to information in other databases

Statistics

Search Criteria

Example Search

Example Results

Osprey Visualization tool Powered by BioGRID Shows graphical relationships between proteins Links to information included in BioGRID

Features Overview Add in known enzymes Shows BioGRID data on the enzyme Visualize links to related enzymes Extended visualization View information on relationship between enzymes Links to database websites with more information

Osprey Example

Osprey Example

Osprey Example

Osprey Example

Osprey Example

Osprey Example

Summary BioGRID sometimes lacking in information, but instead displays error message Very well manicured database Osprey could use a way to find the path between two enzymes A few small UI problems Many useful features