Volume 81, Issue 7, Pages (April 2012)

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Volume 81, Issue 7, Pages 698-706 (April 2012) Comparative effectiveness of incident oral antidiabetic drugs on kidney function Adriana M. Hung, Christianne L. Roumie, Robert A. Greevy, Xulei Liu, Carlos G. Grijalva, Harvey J. Murff, T Alp Ikizler, Marie R. Griffin Kidney International Volume 81, Issue 7, Pages 698-706 (April 2012) DOI: 10.1038/ki.2011.444 Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 1 Flowchart of eligible patients. eGFR, estimated glomerular filtration rate; OAD, oral antidiabetic drug; VA, Veterans Affairs. Kidney International 2012 81, 698-706DOI: (10.1038/ki.2011.444) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 2 Crude cumulative incidence of the composite outcome (persistent reduction of baseline estimated glomerular filtration rate of 25% or end-stage renal disease by oral antidiabetic drug exposure group). Kidney International 2012 81, 698-706DOI: (10.1038/ki.2011.444) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 3 Adjusted hazard ratios for the composite outcome of glomerular filtration rate event or end-stage renal disease among age, race, HbA1c, and renin–angiotensin–aldosterone system blockade subgroups. Hazard ratios greater than 1 demonstrate an increased risk for composite outcome with sulfonylurea compared with metformin. ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker. Kidney International 2012 81, 698-706DOI: (10.1038/ki.2011.444) Copyright © 2012 International Society of Nephrology Terms and Conditions