ACC/AHA 2017 definition of high blood pressure: implications for women with polycystic ovary syndrome Lucas Bandeira Marchesan, B.Sc., Poli Mara Spritzer,

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Presentation transcript:

ACC/AHA 2017 definition of high blood pressure: implications for women with polycystic ovary syndrome Lucas Bandeira Marchesan, B.Sc., Poli Mara Spritzer, M.D., Ph.D. Fertility and Sterility Volume 111, Issue 3, Pages 579-587.e1 (March 2019) DOI: 10.1016/j.fertnstert.2018.11.034 Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Association of homeostasis model assessment insulin resistance (HOMA-IR), insulin, and T levels with phenotypes and systemic arterial hypertension (SAH) according to 2017 American College of Cardiology/American Heart Association (ACC/AHA) criteria. *P<.01 for SAH versus normal blood pressure. Age and body mass index (BMI) were used as covariates in the model. The variables of interest are expressed as means in the y-axis. Two-way analysis of covariance (ANCOVA). DBP = diastolic blood pressure; PCOS = polycystic ovary syndrome; SBP = systolic blood pressure. Fertility and Sterility 2019 111, 579-587.e1DOI: (10.1016/j.fertnstert.2018.11.034) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Correlations of homeostasis model assessment insulin resistance (HOMA-IR), total T (TT), and free androgen index (FAI) with systolic and diastolic blood pressure in the overall group of participants. (A) Systolic blood pressure (SBP). r = 0.36; P<.01 (left panel), r = 0.16; P=.01 (middle panel), r = 0.16; P<.01 (right panel); (B) Diastolic blood pressure (DBP). r = 0.36; P<.01 (left panel), r = 0.22; P<.01 (middle panel), r = 0.33; P<.01 (right panel) Spearman rank correlation test. Fertility and Sterility 2019 111, 579-587.e1DOI: (10.1016/j.fertnstert.2018.11.034) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 3 (A) Frequency of overweight, obesity, and metabolic abnormalities in women with polycystic ovary syndrome (PCOS) and with systemic arterial hypertension (SAH) versus normal blood pressure (NBP) according to 2017 American College of Cardiology/American Heart Association (ACC/AHA) and Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) criteria. BMI = body mass index; HDL = high-density lipoprotein; TG = triglyceride. (B) Prevalence ratios (PR) and 95% confidence intervals (CI) for metabolic parameters in women with PCOS in the presence of SAH versus normal blood pressure according to 2017 ACC/AHA and JNC7 criteria. Fertility and Sterility 2019 111, 579-587.e1DOI: (10.1016/j.fertnstert.2018.11.034) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Frequency of overweight, obesity, and metabolic abnormalities in control women with SAH versus normal blood pressure according to 2017 American College of Cardiology/American Heart Association (ACC/AHA) and Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) criteria. BMI = body mass index; HDL = high-density lipoprotein; NBP = normal blood pressure; SAH = systemic arterial hypertension; TG = triglyceride. Fertility and Sterility 2019 111, 579-587.e1DOI: (10.1016/j.fertnstert.2018.11.034) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions