Abnormalities in sperm acid glycosidases from infertile men with idiopathic oligoasthenoteratozoospermia Juan J Corrales, M.D., Rosa M Burgo, M.D., José.

Slides:

Advertisements

Similar presentations

Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity Cristian O'Flaherty, Ph.D., Barbara.

Advertisements

A new approach to chromosomal abnormalities in sperm from patients with oligoasthenoteratozoospermia: detection of double aneuploidy in addition to single.

Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation Fabio F Pasqualotto,

Evaluation of chemiluminescence and flow cytometry as tools in assessing production of hydrogen peroxide and superoxide anion in human spermatozoa Reda.

Determination of Poly (ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation Rajesh Jha, Ph.D.,

Serum inhibin B may be a reliable marker of the presence of testicular spermatozoa in patients with nonobstructive azoospermia Santiago Brugo-Olmedo,

Marcos Meseguer, Ph. D. , Rebeca Santiso, Ph. D. , Nicolás Garrido, Ph

Seasonal variations and age-related changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration Grace M.

Proteomic analysis of seminal plasma from infertile patients with oligoasthenoteratozoospermia due to oxidative stress and comparison with fertile volunteers

Comparison of fallopian tube sperm perfusion and intrauterine tuboperitoneal insemination: a prospective randomized study Leonidas Mamas, M.D., Ph.D.

Down-regulation of DJ-1 protein in the ejaculated spermatozoa from Chinese asthenozoospermia patients Chun-Na An, M.S., Hui Jiang, M.D., Qi Wang, M.S.,

Relevance of zinc in human sperm flagella and its relation to motility

Gyun Jee Song, Ph.D., Vivian Lewis, M.D. Fertility and Sterility

Evidence of modified nuclear protein matrix in human spermatozoa with fragmented deoxyribonucleic acid Rebeca Santiso, Ph.D., Lourdes Muriel, Ph.D.,

Christopher R Newton, Ph.D., Wendy Sherrard, Irene Glavac

Fertility and Sterility

Ramadan Saleh, M. D. , Reda Z. Mahfouz, M. D. , Ashok Agarwal, Ph. D

Nabil Aziz, Simon Fear, B. Sc. , Clare Taylor, Ph. D

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa

Γ-Aminobutyric acid (GABA) a and b receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone

Detection of oncogenic human papillomavirus genotypes on spermatozoa from male partners of infertile couples Rosaria Schillaci, Ph.D., Giuseppina Capra,

Cysteine-rich secretory protein 1 in seminal plasma: potential biomarker for the distinction between obstructive and nonobstructive azoospermia Christine.

Sperm content of postacrosomal WW binding protein is related to fertilization outcomes in patients undergoing assisted reproductive technology Mahmoud.

Stefan Schanz, M. D. , Thorisa Reimer, M. D. , Martin Eichner, Ph. D

Yuan-qing Yao, M.D., Pak-chung Ho, M.D., William Shu-biu Yeung, Ph.D.

The role of heat shock protein 70 (Hsp 70) in male infertility: is it a line of defense against sperm DNA fragmentation? Gül Özdemirler Erata, Ph.D.,

Varicocele: a bilateral disease

What is the best frame rate for evaluation of sperm motility in different species by computer-assisted sperm analysis? Cesare Castellini, Ph.D., Alessandro.

Levels of the retinoic acid synthesizing enzyme aldehyde dehydrogenase-1A2 are lower in testicular tissue from men with infertility John K. Amory, M.D.,

Evaluation of diagnostic testis biopsy and the repetition of testicular sperm extraction surgeries in infertility patients Alayman Hussein, M.B.B.C.H.,

Armand Zini, M. D. , Gina Defreitas, M. D. , Marc Freeman, B. Sc

Gwo-Jang Wu, M. D. , Ph. D. , Fung-Wei Chang, M. D. , Shang-Sen Lee, M

Fragmentation of DNA in morphologically normal human spermatozoa

Yuan-qing Yao, M.D., Pak-chung Ho, M.D., William Shu-biu Yeung, Ph.D.

Massimo Tartagni, M. D. , Luca Maria Schonauer, M. D

Comparison of two methods for the measurement of sperm concentration

Creatine Kinase Activity in Human Spermatozoa and Seminal Plasma Lacks Predictive Value for Male Fertility in In Vitro Fertilization 1 Claus Rolf, Hermann.

Fertility and Sterility

Alterations in expression of endometrial endothelial nitric oxide synthase and αvβ3 integrin in women with endometriosis Omid Khorram, M.D., Ph.D., Bruce.

Fraction of the peripheral blood concentration of CD56+/CD16−/CD3− cells in total natural killer cells as an indication of fertility and infertility

Microarray analysis in sperm from fertile and infertile men without basic sperm analysis abnormalities reveals a significantly different transcriptome

Preferences for fertility in women with pelvic inflammatory disease

Regulation of assisted reproductive technologies in the United States

Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility Xia Wang, M.D., Ph.D.,

Effect of endometriosis on in vitro fertilization

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

Quantitative evaluation of spermatozoa ultrastructure after acupuncture treatment for idiopathic male infertility Jian Pei, Ph.D., Erwin Strehler, M.D.,

Evaluation of Sperm Proteins in Infertile Men: A Proteomic Approach

Rosalyn D Blumenthal, Ph. D. , Alice P Taylor, Ph. D

Expression of the platelet-activating factor receptor in human spermatozoa: differences in messenger ribonucleic acid content and protein distribution.

Fertility and Sterility

Susanna McReynolds, Ph. D. , Monika Dzieciatkowska, Ph. D

Fertility and Sterility

Matthias Eiss, M.D., Georg Schieferstein, M.D., Richard Wahl, M.D.

Fei Sun, M. D. , Ph. D. , Paul Turek, M. D. , Calvin Greene, M. D

Familial oligoasthenoteratozoospermia: evidence of autosomal dominant inheritance with sex-limited expression Joep H.A.M. Tuerlings, M.D., Ph.D., Ron.

Saad Elzanaty, M.D., Ph.D., Johan Malm, M.D., Ph.D.

William R. Boone, Ph. D. , Jeffrey M. Jones, Ph. D. , Sander S

Microdeletions within the azoospermia factor subregions of the Y chromosome in patients with idiopathic azoospermia Soo Woong Kim, M.D., Ki Dong Kim,

Brooks A. Keel, Ph.D., H.C.L.D.(A.B.B.) Fertility and Sterility

Spermac stain analysis of human sperm acrosomes

DNA damage in patients with untreated cancer as measured by the sperm chromatin structure assay Hiroshi Kobayashi, M.D., Kjersten Larson, M.S., Rakesh.

Juan C. Calamera, Ph. D. , Mariano G. Buffone, Ph. D. , Gustavo F

Multifetal pregnancy in older women and perinatal outcomes

Tamer M. Said, M. D. , Geetha Ranga, M. D. , Ashok Agarwal, Ph. D. , H

Myung-Geol Pang, Ph. D. , Young-Ah You, M. S. , Yoo-Jin Park, M. S

Stephen J Winters, M. D. , Evelyn Talbott, David S Guzick, Ph. D. , M

Absence of deleted in azoospermia (DAZ) genes in spermatozoa of infertile men with somatic DAZ deletions Jan W.A de Vries, Sjoerd Repping, Robert Oates,

How reliable are results from the semen analysis?

Gülşen Aktan, Ph. D. , Semra Doğru-Abbasoğlu, M. D

Presentation transcript:

Abnormalities in sperm acid glycosidases from infertile men with idiopathic oligoasthenoteratozoospermia Juan J Corrales, M.D., Rosa M Burgo, M.D., José M Miralles, M.D., Enrique Villar, Ph.D. Fertility and Sterility Volume 73, Issue 3, Pages 470-478 (March 2000) DOI: 10.1016/S0015-0282(99)00569-5

Figure 1 Relative contribution of glycosidases in the sperm soluble fraction to the total activities (100%) measured in the ejaculate of fertile controls and oligoasthenoteratozoospermic patients. β-glucur (β-glucuronidase), α-mann (α-mannosidase), α-gluc (α-glucosidase), α-galact (α-galactosidase), β-galact (β-galactosidase) and β-NAG (β-N-acetylglucosaminidase). Bars represent means ± SD. ∗P<.05, vs. fertile controls. †P<.01, vs. fertile controls. Corrales. Sperm acid glycosidases. Fertil Steril 2000. Fertility and Sterility 2000 73, 470-478DOI: (10.1016/S0015-0282(99)00569-5)

Figure 2 β-galactosidase and β-N-acetylglucosaminidase activities in the soluble fraction of spermatozoa in fertile controls, oligoasthenoteratozoospermic and azoospermic patients. β-galactosidase activity (upper panel) is expressed in mU/mg of protein (left) or mU/ejaculate (right). β-N-acetylglucosaminidase activity (lower panel) is expressed in mU/mg of protein (left) or mU/ejaculate (right). Bars represent means ± SD. ∗P<.05, vs. fertile controls. †P<.01, vs. fertile controls. Corrales. Sperm acid glycosidases. Fertil Steril 2000. Fertility and Sterility 2000 73, 470-478DOI: (10.1016/S0015-0282(99)00569-5)