Is the kaolin or celite activated clotting time affected by tranexamic acid?  J.F.Matthias Bechtel, MD, Joachim Prosch, Hans-Hinrich Sievers, MD, Claus.

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Is the kaolin or celite activated clotting time affected by tranexamic acid?  J.F.Matthias Bechtel, MD, Joachim Prosch, Hans-Hinrich Sievers, MD, Claus Bartels, MD  The Annals of Thoracic Surgery  Volume 74, Issue 2, Pages 390-393 (August 2002) DOI: 10.1016/S0003-4975(02)03744-X

Fig 1 Measurement of Celite activated clotting time (ACT; ▴) and kaolin activated clotting time (▾) at baseline, after the application of tranexamic acid (TA), and after the application of tranexamic acid and heparin to ex vivo blood samples of healthy volunteers. The application of tranexamic acid alone does not significantly change the baseline activated clotting time. Data are mean ± standard deviation. The Annals of Thoracic Surgery 2002 74, 390-393DOI: (10.1016/S0003-4975(02)03744-X)

Fig 2 Measurement of Celite activated clotting time (ACT; ▴) and kaolin activated clotting time (▾) in patients undergoing primary cardiac operations. No differential effect of tranexamic acid on Celite activated clotting time and kaolin activated clotting time can be observed. Data are mean ± standard deviation. The Annals of Thoracic Surgery 2002 74, 390-393DOI: (10.1016/S0003-4975(02)03744-X)