Progressive Patterned Scalp Hypotrichosis, with Wiry Hair, Onycholysis, and Intermittently Associated Cleft Lip and Palate: Clinical and Genetic Distinction.

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Presentation transcript:

Progressive Patterned Scalp Hypotrichosis, with Wiry Hair, Onycholysis, and Intermittently Associated Cleft Lip and Palate: Clinical and Genetic Distinction from Marie Unna Jack Green, Elizabeth Fitzpatrick, David de Berker, Susan M. Forrest, Rodney D. Sinclair Journal of Investigative Dermatology Symposium Proceedings Volume 8, Issue 1, Pages 121-125 (June 2003) DOI: 10.1046/j.1523-1747.2003.12185.x Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Family pedigree demonstrating autosomal dominant inheritance and intermittent cosegregation with cleft and palate. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 121-125DOI: (10.1046/j.1523-1747.2003.12185.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Bilateral parietal alopecia in VI:2. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 121-125DOI: (10.1046/j.1523-1747.2003.12185.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 3 Hamilton-like alopecia in V:2. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 121-125DOI: (10.1046/j.1523-1747.2003.12185.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 4 Distal onycholysis. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 121-125DOI: (10.1046/j.1523-1747.2003.12185.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 5 Scanning electron microscopy of hairs. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 121-125DOI: (10.1046/j.1523-1747.2003.12185.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions