Application of 5-aminolevulinic acid (5-ALA) induced fluorescence during resection of a brain metastasis. Application of 5-aminolevulinic acid (5-ALA)

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Application of 5-aminolevulinic acid (5-ALA) induced fluorescence during resection of a brain metastasis. Application of 5-aminolevulinic acid (5-ALA) induced fluorescence during resection of a brain metastasis. Parts of the brain metastasis specimen derived from resection (A) can be visualised by 5-ALA-induced fluorescence (B). After surgical resection of the brain metastasis (C), the surrounding, potentially still tumour-infiltrated, brain tissue demonstrates 5-ALA-induced fluorescence (D). Matthias Preusser et al. ESMO Open 2018;3:e000262 Copyright © European Society for Medical Oncology. All rights reserved.