Richard F. Newland, BSc, Robert A. Baker, PhD, Annette L

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Presentation transcript:

Rewarming Temperature During Cardiopulmonary Bypass and Acute Kidney Injury: A Multicenter Analysis Richard F. Newland, BSc, Robert A. Baker, PhD, Annette L. Mazzone, BSc (Hons), Steven S. Quinn, PhD, Derek P. Chew, MBBS, MPH The Annals of Thoracic Surgery Volume 101, Issue 5, Pages 1655-1662 (May 2016) DOI: 10.1016/j.athoracsur.2016.01.086 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flowchart showing patients extracted from Perfusion Downunder Collaborative Database included in analysis. (CKD = chronic kidney disease.) The Annals of Thoracic Surgery 2016 101, 1655-1662DOI: (10.1016/j.athoracsur.2016.01.086) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Duration of arterial perfusion temperatures during cardiopulmonary bypass (CPB) rewarming. Box and whisker plot of cumulative time during CPB that arterial outlet temperature was greater than 36°C, greater than 36.5°C, and greater than 37°C (N = 5,042, 3,900, 1,014, respectively). Box indicates median and interquartile range, upper whisker indicates all data points within 1.5 of the upper quartile stopping at largest value; values greater than this are outliers. The Annals of Thoracic Surgery 2016 101, 1655-1662DOI: (10.1016/j.athoracsur.2016.01.086) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Lowess smoothing plot of mean rewarming temperature greater than 36°C and incidence of acute kidney injury (AKI). Plot confirms that there is an increase in probability of AKI only for temperatures greater than 37°C. The Annals of Thoracic Surgery 2016 101, 1655-1662DOI: (10.1016/j.athoracsur.2016.01.086) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Improvement in compliance with the recommendation by Shann and colleagues (2006) [18] to limit arterial outlet temperature to 37°C during study period in sites contributing to Perfusion Downunder Collaboration. The Annals of Thoracic Surgery 2016 101, 1655-1662DOI: (10.1016/j.athoracsur.2016.01.086) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions