Volume 58, Issue 2, Pages (August 2000)

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Volume 58, Issue 2, Pages 774-782 (August 2000) Evaluation of duplex ultrasound and captopril renography for detection of renovascular hypertension  Mats Johansson, Gert Jensen, Mattias Aurell, Peter Friberg, Hans Herlitz, Hans Klingenstierna, Reinhard Volkmann  Kidney International  Volume 58, Issue 2, Pages 774-782 (August 2000) DOI: 10.1046/j.1523-1755.2000.00226.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Doppler velocity spectra registered downstream from the stenotic lesion within the interlobar renal artery in a stenotic (A and C) and the contralateral kidney (B and D) before (A and B) and one day after (C and D) percutaneous transluminal angioplasty (PTA). Both acceleration of the blood flow during early systole and the pulsatility index (PI) were reduced within the stenotic kidney compared with the contralateral kidney. After PTA, both acceleration and PI within the stenotic kidney increased. Kidney International 2000 58, 774-782DOI: (10.1046/j.1523-1755.2000.00226.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Graph showing the absolute values for the side-to side difference of interlobar renal arteries in patients with normal (< 50% stenosis) renal angiography (N = 98), 50 to 70% stenosis (N = 9), and> 70% stenosis of the renal artery (N = 14). The cut-off values, chosen on the basis of a ≥90% specificity for detection of a renal artery stenosis ≥50 were a PI side difference> 0.20 and an acceleration <2.3 m/s2. Kidney International 2000 58, 774-782DOI: (10.1046/j.1523-1755.2000.00226.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 3 Receiver operating characteristic (ROC) curves (N = 242 kidneys) showing sensitivity for detection of a renal artery stenosis ≥50% vs. 1-specificity for different acceleration (○) and PI (▴) cut-off values. The area under curve was somewhat larger for acceleration of the blood flow compared with the PI side difference criteria. Kidney International 2000 58, 774-782DOI: (10.1046/j.1523-1755.2000.00226.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 4 Graphs showing individual values for (A) single kidney glomerular filtration rate (GFR) estimated by γ camera renography after captopril administration using 99mTc-DTPA and (B) cortical mean transit time. Values for patients with normal (<50% stenosis) renal angiography (N = 79), 50 to 70% stenosis (N = 6), and> 70% stenosis of the renal artery (N = 13) are shown separately. Kidney International 2000 58, 774-782DOI: (10.1046/j.1523-1755.2000.00226.x) Copyright © 2000 International Society of Nephrology Terms and Conditions