Fig. 4. Immunomodulation by TolDCs

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Fig. 4. Immunomodulation by TolDCs Fig. 4. Immunomodulation by TolDCs. Serum levels of total IgE (a) and BtE-specific IgE (B) were measured by ELISA. Relative expression to Gapdh of Gata3 (C) and IL-4 (D) of lung fragments of A strain mice treated with TolDCs previously to allergy induction, by Real-Time PCR. Levels of IFN-γ in the supernatant of splenocyte cultures were evaluated using CBA assay (E). Values are expressed as mean±SEM of 5–8 mice per group, in 1 of the 5 experiments performed. TolDC, tolerogenic dendritic cell; BtE, B. tropicalis mite extract; IgE, immunoglobulin E; ELISA, enzyme-linked immunosorbent assay; PCR, polymerase chain reaction; IFN, interferon; CBA, cytometric bead array; SEM, standard error of the mean. *P<0.05; †P<0.01; ‡P<0.001 (Newman-Keuls multiple comparison test). Fig. 4. Immunomodulation by TolDCs. Serum levels of total IgE (a) and BtE-specific IgE (B) were measured by ELISA. Relative expression to Gapdh of Gata3 (C) and IL-4 (D) of lung fragments of A strain mice treated with TolDCs previously to allergy induction, by Real-Time PCR. Levels of IFN-γ in the supernatant of splenocyte… Allergy Asthma Immunol Res. 2018 Jul;10(4):406-419. https://doi.org/10.4168/aair.2018.10.4.406