A. A. Hislop, PhDa, R. R. Lee, MSb, C. G. A. McGregor, MB, FRCSb, S. G

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Presentation transcript:

Lung Growth After Transplantation Of An Adult Lobe Of Lung Into A Juvenile Rat A.A. Hislop, PhDa, R.R. Lee, MSb, C.G.A. McGregor, MB, FRCSb, S.G. Haworth, FRCP, FACCa The Journal of Thoracic and Cardiovascular Surgery Volume 115, Issue 3, Pages 644-651 (March 1998) DOI: 10.1016/S0022-5223(98)70330-7 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 Photograph of the right lung (RL) and right cardiac lobe (RCL) of a control rat aged 7.5 months and the recipient right lung (RecRL) and transplanted right cardiac lobe (TxRCL) 6 months after transplantation. Bar = 8.5 mm. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 X-ray film of adult rat with airways imaged after a bronchogram 6 months after transplantation. The right lung is displaced into the left hemithorax. All lobes were inflated with air. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Photomicrographs of the alveolar region: A, Transplanted right cardiac lobe 6 months after transplantation. B, Recipient right lung 6 months after transplantation. C, Control lung. D, Pneumonectomized lung. a, alveolus; ad, alveolar duct; br, bronchiolus; p, pleura. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 4 Right lung and right cardiac lobe volume (A) 14 days and (B) 6 months after transplantation and pneumonectomy, together with control values. Mean and standard deviation. *p < 0.01 in comparison with age-matched controls. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 5 Total alveolar number (A) and alveoli per milliliter (B) in the right lung and right cardiac lobe 6 months after the operation. *p < 0.01 in comparison with control. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 6 Diameter of lobar bronchus (A) and terminal bronchioli (B) for the right lung and right cardiac lobe 6 months after the operation. *p = 0.05 in comparison with control. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 644-651DOI: (10.1016/S0022-5223(98)70330-7) Copyright © 1998 Mosby, Inc. Terms and Conditions