A Novel Role for the Fibroblast Growth Factor 21 in Acute Pancreatitis

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A Novel Role for the Fibroblast Growth Factor 21 in Acute Pancreatitis Hana Algül  Gastroenterology  Volume 137, Issue 5, Pages 1577-1579 (November 2009) DOI: 10.1053/j.gastro.2009.09.024 Copyright © 2009 Terms and Conditions

Figure 1 Schematic illustration of the effects of FGF21 during AP. Acinar cell damage results in FGF21 expression. Then, PDGF and subsequent activation of PSCs are inhibited. Furthermore, FGF21 can act as inhibitor of the Egr-1 pathway by acting in a paracrine/autocrine fashion via the βKlotho receptor. Gastroenterology 2009 137, 1577-1579DOI: (10.1053/j.gastro.2009.09.024) Copyright © 2009 Terms and Conditions

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