Volume 87, Issue 1, Pages (January 2015)

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Volume 87, Issue 1, Pages 20-30 (January 2015) Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes  Mark E. Molitch, Amanda I. Adler, Allan Flyvbjerg, Robert G. Nelson, Wing-Yee So, Christoph Wanner, Bertram L. Kasiske, David C. Wheeler, Dick de Zeeuw, Carl E. Mogensen  Kidney International  Volume 87, Issue 1, Pages 20-30 (January 2015) DOI: 10.1038/ki.2014.128 Copyright © 2015 International Society of Nephrology Terms and Conditions

Figure 1 Approaches to improving outcomes related to diabetic kidney disease. The best approach to prevent diabetic kidney disease is to prevent diabetes itself. However, once diabetes occurs glycemic control may prevent/delay the development of diabetic kidney disease. In those patients who develop diabetic kidney disease, glycemic control, blood pressure control, and RAAS inhibition are all important in delaying/decreasing progression to ESRD and glycemic control, blood pressure control, and lipid management are all important in delaying/decreasing the development of CVD. CVD, cardiovascular disease; ESRD, end-stage renal disease; RAAS, renin–angiotensin–aldosterone system. White arrows denote potential preventive measures. Kidney International 2015 87, 20-30DOI: (10.1038/ki.2014.128) Copyright © 2015 International Society of Nephrology Terms and Conditions