A β-glucan receptor is a major receptor for unopsonized zymosan.

Slides:

Advertisements

Similar presentations

Glioma-derived soluble factor(s) enhance IL-10 signaling.

Advertisements

Selective inhibition of BCL10-induced NF-κB activation by Tat–Peptide VIII HEK-293 cells were transiently co-transfected with an expression vector encoding.

Complement Ali Al Khader, MD Faculty of Medicine

A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure by Leanne Stokes, Katrina Scurrah, Justine A. Ellis,

Innate Immunity.

Volume 2, Issue 1, Pages (July 2007)

Figure 1 Pathways of complement activation

Fig. 2. LUM015 fluorescently labels tumor cells in mouse models of STS and breast cancer. LUM015 fluorescently labels tumor cells in mouse models of STS.

A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages by Wei Xia, Andrew R. Hilgenbrink,

by Zhengyan Wang, Tina M. Leisner, and Leslie V. Parise

Volume 27, Issue 2, Pages (August 2007)

Volume 5, Issue 4, Pages (April 2009)

Variations in the composition of mottle patterns.

Phagocytes: Fussy about Carbs

Fig. 4. aPD-1 mAb transfer to macrophages is mediated by FcγRs.

Fungal β-Glucans and Mammalian Immunity

KLK7 is involved in the Aβ degradation activity

Macrophage-specific ablation of Vegfa in PyMT implant tumors blocks blood vessel permeability and tumor cell intravasation at the TMEM. A and C, immunofluorescence.

Increased chemokine content and leukocyte infiltrate in D6-negative tumors. Increased chemokine content and leukocyte infiltrate in D6-negative tumors.

Complement Ali Al Khader, MD Faculty of Medicine

Volume 17, Issue 2, Pages (February 2015)

Volume 18, Issue 5, Pages (January 2017)

Volume 22, Issue 4, Pages (April 2005)

Fig. 2. Top nine proteins differentially expressed between BA and IHC.

ERMES impacts on the exposure of pathogen-associated molecular patterns during hyphal growth. ERMES impacts on the exposure of pathogen-associated molecular.

The fluorescent receptor chains exhibit their characteristic fluorescent signatures: images and spectra of human IFN-γR2/GFP and IFN-γR2/EBFP transfected.

Mixed mutant biofilms have restoration of extracellular matrix structure and function. Mixed mutant biofilms have restoration of extracellular matrix structure.

Volume 5, Issue 5, Pages (May 2009)

2aG4 directly induces monocytic MDSCs to differentiate into dendritic cells and macrophages by binding to phosphatidylserine on their cell surface. 2aG4.

Binding competition between B2′B3 and B3 fragments of TcdB.

Volume 9, Issue 5, Pages (May 2011)

ISS forming highly aggregated structures have decreased capability to induce maturation of human PDCs. Purified PDCs (105 cells) were stimulated with ISS.

CpG-C ISS lose their ability to induce IFN-α from human PDCs while retaining the ability to induce maturation when encapsulated into pH 5.75 liposomes.

CpG-A and CpG-B are distributed in different compartments in PDCs

Volume 21, Issue 10, Pages (October 2014)

Differential intracellular localization of ISS in human PDCs

cMΦ develop into 4 subpopulations after birth.

Stimulation of H2O2 production in L. stagnalis haemocytes by laminarin

The effects of laminarin, PMA and zymosan on PKC phosphorylation.

Fig. 2. DDR1 over-expression enhances collagen fibril reorganization

Effect of 20E on locomotion behavior.

High-affinity binding to the hypervariable region of the β1 I-like domain controls signaling to fibronectin fibrillogenesis. High-affinity binding to the.

Integrin binding of soluble GRGDSP and fibronectin.

Figure 1 Classical pathway and lectin pathway activity in patients with multifocal motor neuropathy and controls Classical pathway (CP) activity (A) and.

ROS production is a component of trained immunity for some stimuli.

Effect of chronic disturbance and an acute handling stressor on hormone receptor expression in testes. Effect of chronic disturbance and an acute handling.

Differential induction of maturation by the different forms of CpG correlates with their ability to promote T cell activation. Differential induction of.

Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased survivin expression. Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased.

Decreased KATP activity for SUR1 (ABCC8) channels harboring R1420H or R1420C mutations. Decreased KATP activity for SUR1 (ABCC8) channels harboring R1420H.

ChREBPα increases β-cell mitochondrial activity and ATP production in human islets. ChREBPα increases β-cell mitochondrial activity and ATP production.

(A) Testosterone (T) and 17β-estradiol (E2) brain levels in control and in d-Asp-treated frogs. (A) Testosterone (T) and 17β-estradiol (E2) brain levels.

Volume 8, Issue 2, Pages (February 1998)

Fig. 1. DEL-1 is expressed by human and mouse osteoclasts.

Fig. 6 RUNX/CBFB interaction inhibitor, Ro5-3335, significantly decreases mouse neurofibroma growth in vivo. RUNX/CBFB interaction inhibitor, Ro5-3335,

Mean fluorescence intensity (MFI) of SIGLEC1 expression before and after introduction of prednisolone or hydroxychloroquine. Mean fluorescence intensity.

A schematic presentation of secreted, endocytic, and signaling pattern-recognition receptors. A schematic presentation of secreted, endocytic, and signaling.

by Babs O. Fabriek, Robin van Bruggen, Dong Mei Deng, Antoon J. M

Individual lipid measures for high-carbohydrate (n=10) and low-carbohydrate (n=10) ultra-endurance athletes. Individual lipid measures for high-carbohydrate.

Estimating statistical significance using the overlap rule for 95% CI bars. Estimating statistical significance using the overlap rule for 95% CI bars.

Incidence of DM as a function of TyG index (white bars) or TG/HDL-C ratio (black bars). Incidence of DM as a function of TyG index (white bars) or TG/HDL-C.

by Fabian C. Verbij, Nicoletta Sorvillo, Paul H. P

Specific DNA methylation and expression signatures associated with binding of E2A–PBX1 fusion protein. Specific DNA methylation and expression signatures.

Fig. 1 Mmp-2 activity is increased in brains after HFD intake.

Small-molecule inhibitor reduced porphyrin production in P

Expression of HO-1 by the FAP+/F4/80+ tumoral macrophages.

A, cellular uptake of AS1411 in MCF-7 and MCF-10A cells.

Fig. 5. Phagocytosis of zymosan particles by BV2 cells

Expression of chemokine receptors in A-498 cell line.

Integrated analysis of gene expression and copy number alterations.

OPN production by immature DCs and mature DCs treated with PAMPs

Presentation transcript:

A β-glucan receptor is a major receptor for unopsonized zymosan. A β-glucan receptor is a major receptor for unopsonized zymosan. The β-glucan, laminarin, specifically inhibits the recognition of unopsonized FITC-labeled zymosan by BMDM (white bars), Tg- (striped bars), and Biogel-elicited macrophages (black bars). The addition of carbohydrates which block the mannose receptor (mannan) and the lectin domain of CR3 (methyl glucoside) had no effect on zymosan binding. The data shown have been normalized to the uninhibited control and expressed as percent relative fluorescence. Gordon D. Brown et al. J Exp Med 2002;196:407-412 © 2002 Rockefeller University Press