Prediction corrected visual predictive check showing observed data concentrations (blue circles) and percentiles (red dashed lines: fifth and 95th percentile,

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Presentation transcript:

Prediction corrected visual predictive check showing observed data concentrations (blue circles) and percentiles (red dashed lines: fifth and 95th percentile, red solid line: 50th percentile) versus time. Prediction corrected visual predictive check showing observed data concentrations (blue circles) and percentiles (red dashed lines: fifth and 95th percentile, red solid line: 50th percentile) versus time. Shaded area reflects the simulated concentrations and the respective 95% CI at the fifth and 95th percentile (black dashed line, blue shading) and 50th percentile (black solid line, pink shading). Joseph E Rower et al. bmjpo 2017;1:e000147 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.