Box plot illustrating the minimum infusion rates of alfaxalone required to prevent movement of extremities in response to noxious stimulation during its co-administration with midazolam: 0.1 mg/kg bolus followed by constant rate infusion (CRI) at 0.1 mg/kg/hour (LMID treatment), 0.3 mg/kg bolus followed by CRI at 0.3 mg/kg/hour (MMID treatment), or 0.9 mg/kg bolus followed by CRI at 0.9 mg/kg/hour (HMID treatment) in goats. Box plot illustrating the minimum infusion rates of alfaxalone required to prevent movement of extremities in response to noxious stimulation during its co-administration with midazolam: 0.1 mg/kg bolus followed by constant rate infusion (CRI) at 0.1 mg/kg/hour (LMID treatment), 0.3 mg/kg bolus followed by CRI at 0.3 mg/kg/hour (MMID treatment), or 0.9 mg/kg bolus followed by CRI at 0.9 mg/kg/hour (HMID treatment) in goats T. B. Dzikiti et al. Vet Rec Open 2015;2:e000065 ©2015 by British Veterinary Association