Case Report: Lymphoma Arising in an Ileal Pouch Anal Anastomosis After Immunomodulatory Therapy for Inflammatory Bowel Disease  Lauren K. Schwartz, Michelle.

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Case Report: Lymphoma Arising in an Ileal Pouch Anal Anastomosis After Immunomodulatory Therapy for Inflammatory Bowel Disease  Lauren K. Schwartz, Michelle Kang Kim, Morton Coleman, Simon Lichtiger, Amy Chadburn, Ellen Scherl  Clinical Gastroenterology and Hepatology  Volume 4, Issue 8, Pages 1030-1034 (August 2006) DOI: 10.1016/j.cgh.2006.05.024 Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 1 Endoscopic appearance of lymphoma within the ileal pouch before (A) and after (B) chemotherapy. Clinical Gastroenterology and Hepatology 2006 4, 1030-1034DOI: (10.1016/j.cgh.2006.05.024) Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 2 (A) Routine histological sections showing the presence of large atypical lymphoid cells with prominent nucleoli (black arrows). Mitotic figures are easily identified (white arrows). Hematoxylin-eosin; original magnification 20×. (B) In situ hybridization for EBV using an EBER probe shows many EBV-infected cells as identified by the dark-brown intranuclear positivity. In situ hybridization; original magnification 40×. Clinical Gastroenterology and Hepatology 2006 4, 1030-1034DOI: (10.1016/j.cgh.2006.05.024) Copyright © 2006 American Gastroenterological Association Terms and Conditions