Epithelial Mesenchymal Interactions in Cancer and Development Alfonso Martinez Arias  Cell  Volume 105, Issue 4, Pages 425-431 (May 2001) DOI: 10.1016/S0092-8674(01)00365-8

Figure 1 Snail Induces EMTs in MDCK Cells (A) MDCK cells in tissue culture. (B) MDCK cells that express the snail gene constitutively. (Images courtesy of M.A. Nieto.) Cell 2001 105, 425-431DOI: (10.1016/S0092-8674(01)00365-8)

Figure 2 Diagram of Possible Ways to Effect an Epithelial Mesenchymal Transition (EMT) Evidence has been collected from tissue culture experiments for each of the steps outlined. There are some good correlations between the expression of Snail and EMTs in vertebrate embryos. The possibility that Wnt signaling has a similar effect in vivo remains to be explored Cell 2001 105, 425-431DOI: (10.1016/S0092-8674(01)00365-8)