Number of ΔFosB-ir cells in the NAc core and shell is dependent on pubertal testosterone and sexual experience. Number of ΔFosB-ir cells in the NAc core.

Slides:

Advertisements

Similar presentations

Glioma-derived soluble factor(s) enhance IL-10 signaling.

Advertisements

DH E2 infusion significantly increased phosphorylation of the p42 isoform of ERK (A) and of Akt (B) in the DH of OVX females, but not sham GDX males. DH.

Activation of PBN and CeA by illuminating the hindpaw after PNI

Active avoidance is impaired in aged mice in both multimodal and visual versions of the task. Active avoidance is impaired in aged mice in both multimodal.

Peptidergic nociceptor markers are reduced in DRG from Nav-Tsc2 mice.

Chemogenetic modulation of vlPAG glutamatergic neurons bidirectionally modulates nociceptive behaviors. Chemogenetic modulation of vlPAG glutamatergic.

Examining effects of different microscopes to image clear brains.

A, Low-magnification (4×) Nissl-stained photomicrograph of the brain tissue section containing the medial ventral striatum depicted in A', outlined by.

Change in mRNA expression of Glasso network genes in differentiated PC12 cells following Caprin2 knockdown or Caprin2 overexpression. Change in mRNA expression.

qRT-PCR validation of differential expression.

Light illumination excites Lamina I SDH neurons after PNI

Expression of Glasso network genes in PC12 cells.

Effects of E2 on levels of phospho-CREB in the DH of OVX females, sham males, and GDX males. Effects of E2 on levels of phospho-CREB in the DH of OVX females,

Neuronal ATM level is reduced in mouse models of AD

Representative photomicrographs of immunohistochemical staining for Wilms’ tumor 1 (WT1) and cleaved caspase-3 in mouse kidney sections at 10, 20, and.

Cross-species comparisons.

Both sexual experience and ΔFosB increase dendritic spines in vmPFC.

Changes in c-Fos expression evoked by the gambling test under the standard or double-reward condition. c-Fos expression was analyzed immunohistochemically.

Task involvement scales change-related potentials A–C, Change-time aligned, central potentials exhibited different profiles across task involvement. Task.

Loss of Cav1 function does not disrupt formation of dual projecting CPN/FPN axonal projections at P8. Loss of Cav1 function does not disrupt formation.

PTX-induced reporter protein expression in the brain of the IEG reporter line. PTX-induced reporter protein expression in the brain of the IEG reporter.

The complexity as well as the total dendritic length of ApoE-deficient adult-born granule cells are significantly reduced. The complexity as well as the.

The complexity and the total dendritic length of ApoE4 adult-born granule cells are significantly reduced. The complexity and the total dendritic length.

CK2 phosphorylates mammalian FMRP S499.

CAV1 is expressed by restricted subpopulations of neocortical neurons at P8, predominantly dual projecting CPN/FPN. CAV1 is expressed by restricted subpopulations.

The adult female mouse ARC and VMH generate newborn neurons that respond to estrogens and leptin. The adult female mouse ARC and VMH generate newborn neurons.

Activation of glial cells.

Effect of FGF8 on R-C marker expression.

Loss of ATF3 function modestly reduces axonal regeneration following sciatic nerve crush. Loss of ATF3 function modestly reduces axonal regeneration following.

CIE does not alter D2/D4 receptor expression in the mPFC.

IL-27 induces expression of multiple IR by CD8+ T cells.

Aβ-mediated Ras-MAPK signaling and Cyclin D1 expression in B103 cells are dependent on APP expression and can be reversed with MEK or Ras inhibition. Aβ-mediated.

Interaction between reboxetine and ADRA2B genotype influences post-treatment symptoms of irritability, anxiety, and dizziness. Interaction between reboxetine.

Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. A,

BNST AVP cell ablations did not change the ability to discriminate between social odors. BNST AVP cell ablations did not change the ability to discriminate.

TeNT did not affect lysosome fusion.

NCS-Rapgef2-dependent ERK activation in mouse NAc following D1 dopamine receptor agonist SKF and psychostimulants D-amphetamine or cocaine administration.

Upon challenge with oxazolone, human leukocytes (mainly consisting of T cells) infiltrate the dermis and epidermis. Upon challenge with oxazolone, human.

Distribution of examined mRNAs across CeA subcompartments.

Identification of the mPOA as a downstream target of AGRP neurons.

Diaphanous regulates the presynaptic actin cytoskeleton.

Overexpression of IL-27 upregulates expression of multiple IR by T cells in vivo. Overexpression of IL-27 upregulates expression of multiple IR by T cells.

PTZ-induced neuronal activity visualized by IEGs

Baseline sex differences in spontaneous excitatory activity.

Use of a PPT to ascertain female preference for males previously exposed to PO relative to CO. A, Schematic representation of the T-maze used for the PPT.

Chronic stress causes a reduction in the neuropil volume occupied by astrocytes in BA but not in dCA3. Chronic stress causes a reduction in the neuropil.

Stress-induced monocyte accumulation in the brain and the neurovascular induction of ICAM-1 were prevented by ADX. Male C57BL/6 mice were subjected to.

Effects of the genotypes of Rapgef2 and Rapgef6 on the distribution of neural progenitor cells. Effects of the genotypes of Rapgef2 and Rapgef6 on the.

A, Cells present in clonal clusters were classified based on morphology (see Materials and Methods) into type 1 progenitor cells (A.1); type 2/3 progenitor.

NestinCre-mediated deletion of CTCF results in activation of caspase-mediated apoptosis. NestinCre-mediated deletion of CTCF results in activation of caspase-mediated.

A, B, Startle magnitude and PPI after treatment with CNO

Elimination of dendritic spines per 2 d.

HFD increased the number of ERα-expressing cells.

Histology and task acquisition.

Effects the genotypes of Rapgef2 and Rapgef6 on RG fiber organization and neuronal migration. Effects the genotypes of Rapgef2 and Rapgef6 on RG fiber.

Cue-evoked dopamine release dynamics in the NAc shell and core.

Optogenetic analysis of mPFC neurons.

Firing rate during consummatory behavior at the early training time point. Firing rate during consummatory behavior at the early training time point. Cells.

Brain ischemic tolerance model using mouse MCAO

Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface structures. Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface.

Thy1S promoter drives sparse expression of hrGFP in marmoset cortex.

Coexpression of Crf and Tac2 (A-P -1.5).

Dynamics of CREB hot spots in the nuclei of living cortical neurons.

A, The ratio of currents elicited by an EC50 concentration of ACh and 100 µm menthol over the current elicited by ACh alone. A, The ratio of currents elicited.

FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression. FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression.

A–C, Schematic representations of experimental timeline (A) and MRI data processing (B, C). A–C, Schematic representations of experimental timeline (A)

PC loss in Nhe6-null mouse cerebellum, female and male.

Expression of Rapgef2 and Rapgef6 in the E13.5 and E15.5 brains.

ΔFosB regulates spike number in hippocampal CA1 neurons.

A, B, 5-HT1A immunoreactivity in hippocampal dendrites (CA3) of saline-treated (A) and fluoxetine-treated (B) rats. A, B, 5-HT1A immunoreactivity in hippocampal.

Presentation transcript:

Number of ΔFosB-ir cells in the NAc core and shell is dependent on pubertal testosterone and sexual experience. Number of ΔFosB-ir cells in the NAc core and shell is dependent on pubertal testosterone and sexual experience. A, Brain atlas (Morin and Wood, 2001) representation of a coronal section containing the NAc. B, Photomicrographs of drawn contours of the NAc onto immunohistochemically-treated tissue sections. The NAc included the shell and core. LV = lateral ventricle; ac = anterior commissure. Scale bar = 250 µm. C, In the core, there was an interaction between pubertal testosterone and sexual experience on ΔFosB-ir cells with sexual experienced T@P males having significantly more ΔFosB-ir cells compared to sexually naive T@P males. There were no significant differences in ΔFosB-ir cells as a function of sexual experience within NoT@P males. In the shell, there was a main effect (ME) of sexual experience on ΔFosB-ir cells with sexually experienced males having more ΔFosB-ir expression compared to sexually naive males. Bars represent mean (±SEM); numbers on bars indicate sample sizes. +Interaction between pubertal testosterone and sexual experience, p ≤ 0.05. Kayla C. De Lorme et al. eNeuro 2019;6:ENEURO.0176-19.2019 ©2019 by Society for Neuroscience