Functional potential analyses.

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Functional potential analyses. Functional potential analyses. (A) HUMAnN2 heat map reporting the 25 most abundant pathways in the fecal samples of mothers and infants. Specific pathways of interest (sugars, mucin, and folate metabolism) are added at the bottom. The asterisk (*) near the heat map highlights statistically significant pathways. (B) Multidimensional scaling (MDS) result from functional potential profiles, showing the differences between fecal samples of mothers and infants and milk samples. In particular, the infant feces point in the mother feces cluster corresponds to time point 3 of pair 5, showing a shift from the infant microbiome toward an adult-like microbiome. (C) HUMAnN2 results for the 25 most abundant pathways found only in the milk samples. TCA, tricarboxylic acid. Francesco Asnicar et al. mSystems 2017; doi:10.1128/mSystems.00164-16