Volume 64, Issue 4, Pages (October 2003)

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Volume 64, Issue 4, Pages 1214-1221 (October 2003) Dietary conjugated linoleic acid reduces PGE2 release and interstitial injury in rat polycystic kidney disease Malcolm R. Ogborn, Evan Nitschmann, Neda Bankovic-Calic, Hope A. Weiler, Shirley Fitzpatrick-Wong, Harold M. Aukema Kidney International Volume 64, Issue 4, Pages 1214-1221 (October 2003) DOI: 10.1046/j.1523-1755.2003.00215.x Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 1 Morphometric assessment of cystic change in heterozygous Han:SPRD-cy rats receiving corn oil (CO) or conjugated linoleic acid (CLA) diets. Kidney International 2003 64, 1214-1221DOI: (10.1046/j.1523-1755.2003.00215.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 2 Morphometric assessment of interstitial fibrosis in heterozygous Han:SPRD-cy rats receiving corn oil (CO) or conjugated linoleic acid (CLA) diets. Kidney International 2003 64, 1214-1221DOI: (10.1046/j.1523-1755.2003.00215.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 3 Morphometric assessment of macrophage infiltration as a measure of inflammation in heterozygous Han:SPRD-cy rats receiving corn oil (CO) or conjugated linoleic acid (CLA) diets. Kidney International 2003 64, 1214-1221DOI: (10.1046/j.1523-1755.2003.00215.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 4 Morphometric assessment of oxidized low-density lipoprotein (ox-LDL) staining in heterozygous Han:SPRD-cy rats receiving corn oil (CO) or conjugated linoleic acid (CLA) diets. Kidney International 2003 64, 1214-1221DOI: (10.1046/j.1523-1755.2003.00215.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 5 Prostaglandin E2 (PGE2) production from renal tissue of healthy (□) and Han:SPRD-cy rats (▪) receiving corn oil or conjugated linoleic acid (CLA) diets. PKD is polycystic disease. *Significantly different from normal animals on same diet, P = 0.014; overall dietary effect, P = 0.022. Kidney International 2003 64, 1214-1221DOI: (10.1046/j.1523-1755.2003.00215.x) Copyright © 2003 International Society of Nephrology Terms and Conditions