Nikole J. Byrne et al. BTS 2017;j.jacbts

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Nikole J. Byrne et al. BTS 2017;j.jacbts.2017.07.003 Improved In Vivo Cardiac Function in Empagliflozin-Treated Mice With Heart Failure Is Preserved Ex Vivo Hearts from vehicle- and Empa-treated mice with HF were perfused ex vivo to measure cardiac function. Cardiac output (A), cardiac work (B), and heart rate (C) were measured using ex vivo perfused working hearts (n = 9 to 10). Results are mean ± SEM. *p < 0.05 versus vehicle, using Mann-Whitney U test. Abbreviations as in Figure 1. Nikole J. Byrne et al. BTS 2017;j.jacbts.2017.07.003 2017 The Authors