Effect of increasing pantetheinase activity in R tumors. Effect of increasing pantetheinase activity in R tumors. (A) Scoring of tumor growth in C57BL/6 mice grafted with R or VR cells and receiving pantethine or a mix of cysteamine and pantothenate every other day during the course of tumor development (n = 6–8 tumors per condition). (B) Comparative growth of R or R/VR chimeric tumors at two different cell ratios grafted in untreated or pantethine-treated mice. Multiple t tests were performed for statistical analysis. Caroline Giessner et al. LSA 2018;1:e201800073 © 2018 Naquet et al.