Performance of electroencephalogram-derived parameters in prediction of depth of anaesthesia in a rabbit model A. Silva, D.A. Ferreira, C. Venâncio,

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Performance of electroencephalogram-derived parameters in prediction of depth of anaesthesia in a rabbit model A. Silva, D.A. Ferreira, C. Venâncio, A.P. Souza, L.M. Antunes British Journal of Anaesthesia Volume 106, Issue 4, Pages 540-547 (April 2011) DOI: 10.1093/bja/aeq407 Copyright © 2011 The Author(s) Terms and Conditions

Fig 1 Prediction probabilities (Pks) for the studied indices: IoC, index of consciousness; PE, permutation entropy; AE, approximate entropy; MEF, median edge frequency; SEF, spectral edge frequency 95%; BSPE, burst suppression corrected PE; BSMEF, BS corrected MEF; and BSSEF, BS corrected SEF. Each animal’s Pk value is shown by a symbol (n=6). British Journal of Anaesthesia 2011 106, 540-547DOI: (10.1093/bja/aeq407) Copyright © 2011 The Author(s) Terms and Conditions

Fig 2 Indices computed from the EEG (n=6) at different study times: T0, baseline recording; T1, 1 min after fentanyl administration; T2, right before intubation; T3, when the ear pinch reflex was lost; T4, 1 min before incision; T5, 1 min after incision; T6, 5 min after incision; T7, 10 min after incision; T8, end of surgery; T9, at extubation; T10, regaining ambulation. (a) IoC, index of consciousness; (b) Burst suppression ratio (BS, %); (c) PE, permutation entropy (green line) and BSPE, burst suppression corrected PE (blue line); (d) AE, approximate entropy; (e) MEF, median edge frequency (green line) and BSMEF, BS corrected MEF (blue line), and (f) SEF, spectral edge frequency 95% (green line) and BSSEF, BS corrected SEF (blue line). Mean and standard deviation of the mean are presented. Statistically significant differences from the previous measurement: ***P<0.001; **P<0.01; *P<0.05. British Journal of Anaesthesia 2011 106, 540-547DOI: (10.1093/bja/aeq407) Copyright © 2011 The Author(s) Terms and Conditions