Changbin Qiu, Chris Baylis Kidney International

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Endothelin and angiotensin mediate most glomerular responses to nitric oxide inhibition Changbin Qiu, Chris Baylis Kidney International Volume 55, Issue 6, Pages 2390-2396 (June 1999) DOI: 10.1046/j.1523-1755.1999.00466.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 The percentage change in mean arterial blood pressure (BP), mean glomerular blood pressure (PGC), afferent and efferent arteriolar resistances (RA and RE, respectively), and the glomerular capillary ultrafiltration coefficient (Kf) in the normal anesthetized rat. Rats received acute systemic NO synthesis inhibition (NOSI) alone, with NMA (group I), combined endothelin blockade of ETA and ETB receptors and NOSI with bosentan and NMA (group II), combined NOSI and angiotensin II AT1 receptor blockade with losartan and NMA (group III), and NOSI during combined ETA, ETB, and AT1 receptor blockade (group IV). The asterisk denotes a significant difference in the response versus NOSI alone. Kidney International 1999 55, 2390-2396DOI: (10.1046/j.1523-1755.1999.00466.x) Copyright © 1999 International Society of Nephrology Terms and Conditions