Lawrence Ko, BS, Andrew Maitland, MD, Paul W

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Presentation transcript:

Endothelin blockade potentiates endothelial protective effects of ace inhibitors in saphenous veins Lawrence Ko, BS, Andrew Maitland, MD, Paul W.M Fedak, MD, Aaron S Dumont, MD, Mitesh Badiwala, BS, Fina Lovren, PhD, Christopher R Triggle, PhD, Todd J Anderson, MD, Vivek Rao, MD, PhD, Subodh Verma, MD, PhD The Annals of Thoracic Surgery Volume 73, Issue 4, Pages 1185-1188 (April 2002) DOI: 10.1016/S0003-4975(01)03605-0

Fig 1 Endothelium-dependent vascular relaxation to acetylcholine in saphenous veins from untreated and angiotensin converting enzyme inhibitor-treated groups. Percentage maximum relaxatory responses to acetylcholine (%Emax) in vessel rings precontracted with the concentration that evoked 75% of maximum contraction to phenylephrine are depicted and compared between groups. ∗p < 0.05, different from all other groups; ∗∗p < 0.05, different from all other groups. (ACh = acetylcholine.) The Annals of Thoracic Surgery 2002 73, 1185-1188DOI: (10.1016/S0003-4975(01)03605-0)