Peritoneal fluid concentrations of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta in women with.

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Presentation transcript:

Peritoneal fluid concentrations of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta in women with pelvic adhesions Ying C Cheong, MB, BCh, Jenny B Shelton, PhD, Susan M Laird, PhD, Tin-Chiu Li, PhD, FRCOG, William L Ledger, PhD, F.R.C.O.G., Ian D Cooke, PhD, F.R.O.C.G. Fertility and Sterility Volume 79, Issue 5, Pages 1168-1175 (May 2003) DOI: 10.1016/S0015-0282(03)00079-7

FIGURE 1 MMP-9 concentrations in women with and without pelvic adhesions. (A), Follicular phase. (B), Luteal phase. (*P <.01). Cheong. MMP-9, TIMP-1, and TGF-β in pelvic adhesions. Fertil Steril 2003. Fertility and Sterility 2003 79, 1168-1175DOI: (10.1016/S0015-0282(03)00079-7)

FIGURE 2 Ratio of peritoneal fluid concentrations during the first 48 hours after surgery. Solid line: More than 10% adhesions reformed. Dashed line: Less than 10% adhesions reformed. (A), MMP-9/TIMP-1. (B), MMP-9. (C), TIMP-1. (*P <.05.) Cheong. MMP-9, TIMP-1, and TGF-β in pelvic adhesions. Fertil Steril 2003. Fertility and Sterility 2003 79, 1168-1175DOI: (10.1016/S0015-0282(03)00079-7)

FIGURE 3 (A–D), Peritoneal fluid concentrations before and after adhesiolysis. (A), MMP-9. (B), TIMP-1. (C), MMP-9/TIMP-1 ratio. (D), TGF-β. (*P <.05, **P <.01). Cheong. MMP-9, TIMP-1, and TGF-β in pelvic adhesions. Fertil Steril 2003. Fertility and Sterility 2003 79, 1168-1175DOI: (10.1016/S0015-0282(03)00079-7)