The impact of chronic endometritis on reproductive outcome

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Presentation transcript:

The impact of chronic endometritis on reproductive outcome Jenneke C. Kasius, M.D., Human M. Fatemi, M.D., Ph.D., Claire Bourgain, M.D., Ph.D., Daisy M.D.S. Sie-Go, M.D., Ph.D., René J.C. Eijkemans, Ph.D., Bart C. Fauser, M.D., Ph.D., Paul Devroey, M.D., Ph.D., Frank J.M. Broekmans, M.D., Ph.D. Fertility and Sterility Volume 96, Issue 6, Pages 1451-1456 (December 2011) DOI: 10.1016/j.fertnstert.2011.09.039 Copyright © 2011 Terms and Conditions

Figure 1 Flow chart illustrating the selection of cases used for the analysis of the IVF treatment outcome. Cases diagnosed with chronic endometritis were matched with a sample of randomly selected patients not diagnosed with chronic endometritis. Matching was performed by research center and day of menstrual cycle on which the endometrial biopsy was obtained.a The trial “Treatment Efficacy of unsuspected uterine Abnormalities” on subsequent in vitro fertilization (IVF) or intra cytoplasmic sperm injection (ICSI) treatment (register number: NCT00830401); b Most patients did not start IVF/ICSI treatment due to personal reasons. One patient did not start because of spontaneous pregnancy resulting in a live birth; c Including 3 patients who had a spontaneous pregnancy resulting in a live birth (of whom one did not undergo IVF/ICSI treatment) and 4 patients, who had an early miscarriage before the live birth; d Including 11 patients who had an early miscarriage and did not become pregnant afterwards and one patient, who had a preterm delivery at 22 weeks gestation; e The final outcome after IVF/ICSI remained unknown. After a sonography at 8 weeks gestation - which showed an intact intrauterine twin pregnancy- no record was kept. Fertility and Sterility 2011 96, 1451-1456DOI: (10.1016/j.fertnstert.2011.09.039) Copyright © 2011 Terms and Conditions

Figure 2 Survival curve showing the cumulative live birth rate in consecutive embryo cycles for the cases with endometritis compared with those without endometritis, including spontaneous pregnancies resulting in a live birth (control). Fertility and Sterility 2011 96, 1451-1456DOI: (10.1016/j.fertnstert.2011.09.039) Copyright © 2011 Terms and Conditions