Volume 57, Issue 6, Pages (June 2000)

Slides:

Advertisements

Similar presentations

Reduced renal function in patients with simple renal cysts

Advertisements

Volume 65, Issue 6, Pages (June 2004)

Quiz Page June 2007 American Journal of Kidney Diseases

Volume 81, Issue 11, Pages (June 2012)

A powerful new agonist: flooding the system with growth hormone

Renal manifestations in Fabry disease and therapeutic options

Volume 68, Issue 6, Pages (December 2005)

J.M. Henderson, S. al-Waheeb, A. Weins, S.V. Dandapani, M.R. Pollak

Volume 61, Issue 2, (February 2002)

Volume 75, Issue 11, Pages (June 2009)

Volume 71, Issue 8, Pages (April 2007)

Karl A. Nath, Anthony J. Croatt, Jill J. Haggard, Joseph P. Grande

PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice

Volume 57, Issue 5, Pages (May 2000)

Proinflammatory effects of iron sucrose in chronic kidney disease

Punit Yadav, Nelson Leung, Paul W. Sanders, Paul Cockwell

Volume 63, Issue 4, Pages (April 2003)

G.S. Markowitz, C. Gelber, V.D. D'agati Kidney International

D. Coyne Kidney International Volume 69, Pages S1-S3 (May 2006)

Growth hormone promotes glomerular lipid accumulation in bGH mice

Volume 72, Issue 4, Pages (August 2007)

Volume 66, Issue 1, Pages (July 2004)

Volume 70, Issue 12, Pages (December 2006)

Ferruh Artunc, Friedhelm Hildebrandt, Kerstin Amann

Infected glomerulus Kidney International

Therapy of relapsing minimal-change disease in adults: a new approach?

Volume 65, Issue 6, Pages (June 2004)

Volume 82, Issue 1, Pages 3-4 (July 2012)

An unusual cause of acute renal failure

Volume 79, Issue 8, Pages (April 2011)

Hypertension, race, and glomeruli: more than simply a numbers game

The third World Kidney Day: Looking back and thinking forward

Volume 66, Issue 5, Pages (November 2004)

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 67, Issue 3, Pages (March 2005)

Nephrology Crossword: Peritoneal Dialysis

Red cell traverse through thin glomerular basement membranes

Volume 55, Issue 3, Pages (March 1999)

Reduced renal function in patients with simple renal cysts

Nephrology Crossword: Glomerulonephritis

Quiz Page November 2006 American Journal of Kidney Diseases

The initiation and progression of sickle cell nephropathy

Fibrosis and renal aging

Volume 80, Issue 7, Pages (October 2011)

It's not over till the last glomerulus forms

TGF-β type II receptor deficiency prevents renal injury via decrease in ERK activity in crescentic glomerulonephritis C.Y. Song, B.C. Kim, H.K. Hong,

H. Raffi, J.M. Bates, Z. Laszik, S. Kumar Kidney International

The course of the remnant kidney model in mice

Organ transplantation goes to the movies

The vascular secret of Klotho

Class IV-S versus class IV-G lupus nephritis: Clinical and morphologic differences suggesting different pathogenesis Gary S. Hill, Michel Delahousse,

Volume 80, Issue 10, Pages (November 2011)

Quiz Page June 2009 American Journal of Kidney Diseases

Volume 71, Issue 9, Pages (May 2007)

The Case ∣ An Asian boy with proteinuria

Volume 62, Issue 5, (November 2002)

Miguel G. Salom, Bárbara Bonacasa Kidney International

The international realities of live donor kidney transplantation

Quiz Page March 2009 American Journal of Kidney Diseases

The Case ∣ A Senegalese man with gross hematuria

Volume 74, Issue 10, Pages (November 2008)

Volume 75, Issue 8, Pages (April 2009)

Glomerular monocytes predict worse outcomes after acute renal allograft rejection independent of C4d status Kathryn J. Tinckam, Ognjenka Djurdjev, Alex.

Volume 56, Issue 6, Pages (December 1999)

Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease T.A.O. Jiang,

Quiz page December 2003 American Journal of Kidney Diseases

Volume 56, Issue 6, Pages (December 1999)

Decreased urinary excretion of vascular endothelial growth factor in idiopathic membranous glomerulonephritis Eero O. Honkanen, Anna-Maija Teppo, Carola.

Alex B. Magil, Kathryn Tinckam Kidney International

Presentation transcript:

Volume 57, Issue 6, Pages 2299-2307 (June 2000) Glomerulosclerosis in mice transgenic for human insulin-like growth factor-binding protein-1 Sophie Doublier, Danielle Seurin, Bruno Fouqueray, Marie-Christine Verpont, Patrice Callard, Liliane J. Striker, Gary E. Striker, Michel Binoux, Laurent Baud Kidney International Volume 57, Issue 6, Pages 2299-2307 (June 2000) DOI: 10.1046/j.1523-1755.2000.00090.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Light micrographs of a glomerulus from homozygous transgenic mice (A), heterozygous transgenic mice (B), and nontransgenic mice (C). All mice were three months old (PAS stain, final magnification ×400). Kidney International 2000 57, 2299-2307DOI: (10.1046/j.1523-1755.2000.00090.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Light micrographs of a glomerulus from homozygous transgenic mice (A) and nontransgenic mice (B). All mice were three months old. PAS-positive materials in the vascular pole are indicated by an arrow. Magnification is ×400. Kidney International 2000 57, 2299-2307DOI: (10.1046/j.1523-1755.2000.00090.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 3 Immunochemistry micrographs of a glomerulus stained by mAb that was reactive with laminin (first column), type IV collagen (second column), or type I collagen (third column). (A, B, and C) Homozygous transgenic mice. (D, E, and F) Nontransgenic mice. All mice were three months old. Magnification is ×400. Kidney International 2000 57, 2299-2307DOI: (10.1046/j.1523-1755.2000.00090.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 4 Electron microscopic photograph of a glomerulus from homozygous transgenic mice (A) and nontransgenic mice (B). All mice were three months old (×14,000). Kidney International 2000 57, 2299-2307DOI: (10.1046/j.1523-1755.2000.00090.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 5 Plasma concentrations of GH in homozygous transgenic mice, heterozygous transgenic mice, and nontransgenic mice of three months of age. The baseline indicates the limit of sensitivity of the assay. Kidney International 2000 57, 2299-2307DOI: (10.1046/j.1523-1755.2000.00090.x) Copyright © 2000 International Society of Nephrology Terms and Conditions