Efficacy and duration of antistaphylococcal activity comparing three antibiotics bonded to Dacron vascular grafts with a collagen release system Arun.

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Presentation transcript:

Efficacy and duration of antistaphylococcal activity comparing three antibiotics bonded to Dacron vascular grafts with a collagen release system Arun Chervu, MD, Wesley S. Moore, MD, Milos Chvapil, MD, PhD, DSc, Theodore Henderson, BS Journal of Vascular Surgery Volume 13, Issue 6, Pages 897-901 (June 1991) DOI: 10.1016/0741-5214(91)90057-2 Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 This compares the area of bacterial inhibition on a blood agar plate as a function of time that the graft has been soaking in solution before testing. The curves for chloramphenicol palmitate bonded with collagen, amikacin bonded with collagen, rifampin in a blood preclot, and rifampin bonded to grafts with collagen are compared. The best and longest result occurred with rifampin bonded with collagen. This was statistically better and for a longer duration than the other two antibiotics bonded with collagen or rifampin mixed in a blood preclot. Journal of Vascular Surgery 1991 13, 897-901DOI: (10.1016/0741-5214(91)90057-2) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions