Expression of pcdh19 in BAC transgenic line.

Slides:

Advertisements

Similar presentations

From Fig. 1: Photographs of a finished preparation illuminated with transmitted light. The box in i indicates the areas magnified in ii and iii. (ii) shows.

Advertisements

The Habenula Prevents Helpless Behavior in Larval Zebrafish

DESCRIBING NEUROPIL REGIONS IN THE ZEBRAFISH BRAIN

Bifocal Is a Downstream Target of the Ste20-like Serine/Threonine Kinase Misshapen in Regulating Photoreceptor Growth Cone Targeting in Drosophila Wenjing.

Volume 26, Issue 2, Pages (January 2016)

Alessandra Maria Casano, Marvin Albert, Francesca Peri Cell Reports

Density of dendritic spines on L2/3 pyramidal neurons is greater in visual cortex of germline PirB−/− mice than in PirB+/+ mice at P30. Density of dendritic.

Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine Jin Xu, Tienan Wang, Yi Wu, Wan Jin,

Volume 27, Issue 2, Pages (January 2017)

Volume 87, Issue 6, Pages (September 2015)

Real-Time Visualization of Neuronal Activity during Perception

Pathfinding and Error Correction by Retinal Axons

Volume 8, Issue 6, Pages (September 2014)

Distribution and functionality of Arch-EGFP pumps in the peripheral sensory pathways of Nav1.8-Arch+ mice. Distribution and functionality of Arch-EGFP.

Volume 8, Issue 4, Pages (August 2014)

Alessandra Maria Casano, Marvin Albert, Francesca Peri Cell Reports

Volume 22, Issue 5, Pages (May 2012)

Volume 23, Issue 10, Pages (May 2013)

Volume 9, Issue 4, Pages (November 2014)

Structure and Function of an Actin-Based Filter in the Proximal Axon

Volume 23, Issue 10, Pages (May 2013)

A, Low-magnification (4×) Nissl-stained photomicrograph of the brain tissue section containing the medial ventral striatum depicted in A', outlined by.

Optogenetic stimulation of neuronal repair

Volume 87, Issue 6, Pages (September 2015)

Julie E. Cooke, Hilary A. Kemp, Cecilia B. Moens Current Biology

Pranav Sharma, Hollis T. Cline Neuron

Upper cortical layer-enriched neuronal expression of HA-UPRT.

Neuronal ensembles in optic tectum microcircuits.

Identification of one type of RGCs with large somas.

Volume 18, Issue 3, Pages (March 2010)

HDAC4N increases with Braak stage in CA2 hippocampal pyramidal cells.

Intralineage Directional Notch Signaling Regulates Self-Renewal and Differentiation of Asymmetrically Dividing Radial Glia Zhiqiang Dong, Nan Yang, Sang-Yeob.

Volume 13, Issue 10, Pages (May 2003)

Temporally Regulated Asymmetric Neurogenesis Causes Left-Right Difference in the Zebrafish Habenular Structures Hidenori Aizawa, Midori Goto, Tomomi.

Altered development of small-worldness in pcdh19 mutants.

Development of basic network properties in wild-type and pcdh19 mutant larvae. Development of basic network properties in wild-type and pcdh19 mutant larvae.

Islet Coordinately Regulates Motor Axon Guidance and Dendrite Targeting through the Frazzled/DCC Receptor Celine Santiago, Greg J. Bashaw Cell Reports

Developmental changes in transitivity in pcdh19 mutants.

Developmental time course of network measures.

Development of assortativity in wild-type and pcdh19 mutant larvae.

MET activation increases the density of Syn-GFP/bassoon and Syn-GFP/PSD-95 clusters in neocortical neurons. MET activation increases the density of Syn-GFP/bassoon.

Fig. 8. The morphology of the ventral nerve cord in Ror-Myc overexpressing embryos is normal. The morphology of the ventral nerve cord in Ror-Myc overexpressing.

Two-photon imaging of GCaMP6s in zebrafish larvae.

Protein expression of EAAT2 paralogs.

Loss of Cav1 function does not disrupt formation of dual projecting CPN/FPN axonal projections at P8. Loss of Cav1 function does not disrupt formation.

PTX-induced reporter protein expression in the brain of the IEG reporter line. PTX-induced reporter protein expression in the brain of the IEG reporter.

Activation of Intrinsic Growth State Enhances Host Axonal Regeneration into Neural Progenitor Cell Grafts Hiromi Kumamaru, Paul Lu, Ephron S. Rosenzweig,

CAV1 is expressed by restricted subpopulations of neocortical neurons at P8, predominantly dual projecting CPN/FPN. CAV1 is expressed by restricted subpopulations.

The adult female mouse ARC and VMH generate newborn neurons that respond to estrogens and leptin. The adult female mouse ARC and VMH generate newborn neurons.

Single-Cell Electroporationfor Gene Transfer In Vivo

Fig. 1. Expression of a Ror-eGFP fusion protein under control of the endogenous Ror promoter in Drosophila embryos. Expression of a Ror-eGFP fusion protein.

RA signaling in early postnatal PFC

SiRNA directed at Ngn1 inhibited differentiation of inner ear stem cells to β-III tubulin-positive cells. a, Inner ear stem cells treated with siRNA to.

GFP is expressed selectively in NPY neurons.

Katsuhiko Ono, Yukihiko Yasui, Urs Rutishauser, Robert H Miller Neuron

Localization of thalamic terminals and corticocollicular pyramidal neurons in layer 5 of the AC. A, Diagram of triple virus injection into the IC, MGB,

Phosphorylation of β-catenin at Y142 is required for the HGF-induced increase in Syn-GFP/bassoon and Syn-GFP/PSD-95 clusters. Phosphorylation of β-catenin.

Effects of the genotypes of Rapgef2 and Rapgef6 on the distribution of neural progenitor cells. Effects of the genotypes of Rapgef2 and Rapgef6 on the.

Expression of p130CAS in primary culture neurons

Identification of a novel subset of mDA neurons in the VTA that expresses Neurod6, OTX2, CALBINDIN1, ALDH1A1, and Grp. Identification of a novel subset.

Topographic organization of CA3 to CA1 projections revealed through monosynaptic rabies tracing by specifically targeting CA1 pyramidal cells along the.

Knock-out of NSG2 decreases mEPSC frequency.

Selective expression of Neurod6 in mDA neurons in the VTA

Optogenetic analysis of mPFC neurons.

3D visualization of fluoro-Ruby-labeled CST axons in cleared nonhuman primate spinal cord. 3D visualization of fluoro-Ruby-labeled CST axons in cleared.

Targeting β-actin and GAP-43 mRNAs into axons using the STAT3α 3′UTR selectively modulates axonal growth phenotypes. Targeting β-actin and GAP-43 mRNAs.

A tph2 promoter fragment labels DR serotonergic neurons.

TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal region. TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal.

Spatial distribution of node-based measures in a 6 dpf larva.

BDNF protein is expressed in neurons and astrocytes of hippocampus after pilocarpine-induced SE. A, Representative confocal images of hippocampal subfields.

Presentation transcript:

Expression of pcdh19 in BAC transgenic line. Expression of pcdh19 in BAC transgenic line. A–C, Distribution of pcdh19 expression in the midbrain and hindbrain of TgBAC(pcdh19:Gal4-VP16, 5xUAS:Lifeact-GFP) larvae at 4 dpf. In addition to neurons and neural progenitor cells, pcdh19 is expressed in the neurovasculature and epithelia within the developing ear. A, In the ventral brain, Lifeact-GFP labels both longitudinal (yellow arrow) and commissural axon bundles. B, Expression is evident in a bilateral cluster of neurons in the anterior hindbrain, which likely correspond to the ARTR (yellow regions). C, pcdh19 is also present in limited clusters of neurons in the hindbrain (blue, magenta and yellow regions) and optic tectum (green region). D–F, Higher magnification images show that within those regions that express pcdh19, it is present in only a fraction of neurons. D, As shown previously, pcdh19 is expressed in radial columns of neurons within the optic tectum (yellow arrows). E, In addition to the ARTR, pcdh19 labels bilateral clusters of neurons. F, In the ventral midbrain, pcdh19 labels small clusters of radial glia (yellow arrow), as well as neurons, axon tracts and vasculature. Scale bars = 125 μm (A–C), 50 μm (D, F), and 63 μm (E). Sarah E.W. Light, and James D. Jontes eNeuro 2019;6:ENEURO.0420-18.2019 ©2019 by Society for Neuroscience