Building groupings based on culture density, diversity, and drug resistance phenotypes. Building groupings based on culture density, diversity, and drug.

Slides:

Advertisements

Similar presentations

Enrichment of sequence disorder in the cytosolic phosphoproteome.

Advertisements

Boxplots displaying relative percent abundance of consistent abundance-based microbiome members present in the tissue, mucus, and holobiont (Holo) fractions.

NF1 silencing confers resistance of PC9 lung adenocarcinoma cells to erlotinib (erl). NF1 silencing confers resistance of PC9 lung adenocarcinoma cells.

H-NS2 protein interacts with Lon and H-NS protein in vitro.

Heatmap displaying consistent similarity-based OTU results based on SIMPER intragroup similarity analyses for the tissue, mucus, holobiont, and seawater.

Heatmap summarizing the significant (P < 0

Fig. 6 Bimodal treatment results in reduced tinnitus loudness and reduced TFI scores in human patients. Bimodal treatment results in reduced tinnitus loudness.

Blooms and effect sizes.

H-NS2 is upregulated in an hns mutant derivative of the strain E

Phenotype validation: a novel heat shock function for the copper-responsive regulator CopR. Phenotype validation: a novel heat shock function for the copper-responsive.

Jason A. Bartos et al. BTS 2016;j.jacbts

Boxplots of βNTI distribution in the Mollisol (A), Inceptisol (B), and Ultisol (C) soil types. Boxplots of βNTI distribution in the Mollisol (A), Inceptisol.

Fluoride affects stool-derived taxa found in the oral cavity.

The HIV protease and PI3K/Akt inhibitor nelfinavir does not improve the curative effect of fractionated irradiation in PC-3 prostate cancer in vitro and.

Lack of phylogenetic conservatism of Bacillus anthracis plasmid copy number. Lack of phylogenetic conservatism of Bacillus anthracis plasmid copy number.

Fig. 1. Drug combination screen identifies BETi as acting synergistically with PARPi. Drug combination screen identifies BETi as acting synergistically.

Fig. 2 Identification of the candidate AvrSr35 gene.

Gene-wise Tajima’s D values and gene lengths.

Pairwise analysis of detected virus taxonomy prior to and following intervention. Pairwise analysis of detected virus taxonomy prior to and following intervention.

Synthetic perturbation of DE and DV genes.

Target identification of ampicillin and ciprofloxacin

Bacterial community dissimilarity, as measured by weighted UniFrac, a quantitative measurement (a), and unweighted UniFrac, a qualitative measurement (b),

SEM images of organisms on microplastic particle surfaces.

Phenotype gain and loss dynamics match protein family dynamics.

Enterotypes of the distal gut microbial profiles.

Patient organoids respond more diverse to drugs and with lower therapeutic potential than 2D cultured patient cells Patient organoids respond more diverse.

Phenotypic variation of sake yeast strains.

Outgrowth of passaged strains.

IBD development correlates with peripheral T cell activation in DNR mice. IBD development correlates with peripheral T cell activation in DNR mice. (A)

Implicit adaptation generalizes around the aiming location (30° CCW)

A, Multivariate glm analysis for the aggregate observer (for the interval range within –450 and 250 ms from action execution). A, Multivariate glm analysis.

Fig. 3. TKI sensitivity assessed by the MANO method.

Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss S.N. Edd, J. Favre,

Label frequency and average enrichment of taxa.

Enrichment of microbial functions with elevated triclosan.

Dynamics of the model. Dynamics of the model. (A) Snapshot of a simulation. At this time, the population has adapted to the drug concentrations in compartments.

Single-cell phenotyping with Traitar.

(A) Box-and-whisker plots illustrate the median, maximum, minimum, and first and third quartiles of the distribution of the number of observed OTUs and.

Alterations in Notch signaling affect the frequency of intermediate and main IHBD branches. Alterations in Notch signaling affect the frequency of intermediate.

Fig. 4. A primary screen based on scrape closure

OA and related amines modulate motility and length of schistosomula.

Benchmarks of OTU picking tools on artificial communities.

Fig. 2. Kinetics of OptoEphB2 activation.

CaQTL analysis identifies genetic variants affecting human islet cis-RE use. caQTL analysis identifies genetic variants affecting human islet cis-RE use.

Blocking actin turnover affects AJ remodeling and E-cad dynamics.

N fluxes during N. europaea culture.

(a) Molecular network clusters of pheophytin and procyanidin and their related metabolites. (a) Molecular network clusters of pheophytin and procyanidin.

E. coli CFT073 and E. coli MG1655 persistence.

Differences in Verrucomicrobia genera across plant community types.

Vessel density is decreased in tumors grown in Fbln5−/− mice.

Phylogenetic diversity (PD) by signiﬁcant market integration factors, house modernity (A), power usage (B), and house modernity and power usage (C). Phylogenetic.

Aplf knockdown does not compromise DNA repair competency in iPSCs.

Subcategorical structure within animate and inanimate categories in TEO, TE, and PFC. a, The bar graphs show the mean dissimilarities (percentile of 1.

KEGG categories of host DEGs (up- and downregulated genes) enriched at selected points after φAbp1 infection. KEGG categories of host DEGs (up- and downregulated.

Elimination of dendritic spines per 2 d.

Estimating statistical significance using the overlap rule for 95% CI bars. Estimating statistical significance using the overlap rule for 95% CI bars.

Relationships between antimicrobial chemicals, features of the built environment, and microbial communities. Relationships between antimicrobial chemicals,

Relationships between biocide concentrations and microbial species.

Effect of siltuximab on paclitaxel sensitivity in ovarian cancer drug resistant cells. Effect of siltuximab on paclitaxel sensitivity in ovarian cancer.

Activation status of CD8+ T cells.

Knockdown of NR2A and NR2B leads to distinct rearrangements of the dendritic arbor architecture. Knockdown of NR2A and NR2B leads to distinct rearrangements.

Fig. 1. Dysbiosis of the skin microbiome in AD is associated with S

Variations in beta and alpha diversity of gut microbiome bacterial communities in relation to presence of Blastocystis. Variations in beta and alpha diversity.

Variations in beta and alpha diversity of gut microbiome eukaryotic communities explained by presence of Blastocystis. Variations in beta and alpha diversity.

Targeted bile acid metabolomics of murine ileal and cecal contents.

Median unweighted UniFrac distances between three dolphin habitats: Shedd, MMP, and Sarasota. Median unweighted UniFrac distances between three dolphin.

Impact of the SOS activities on E. coli mutation rates.

Phenotypic diversity of less predominant B-lineage clones.

Dietary choline is required for TMAO accumulation.

Fig. 4 Gallium increases P. aeruginosa sensitivity to peroxides.

Presentation transcript:

Building groupings based on culture density, diversity, and drug resistance phenotypes. Building groupings based on culture density, diversity, and drug resistance phenotypes. (a) Mean triclosan concentrations (error bars ± 2 SEM) per building level, with colors as in Fig. 1d. Median and quartiles are shown for a large significant cluster of similar buildings (identified in panels b and c). (b) Colony-forming unit (CFU) densities g−1 dust and the fractions of CFUs resistant to clarithromycin, ampicillin, and tetracycline. (c) Cluster dendrogram showing Gower dissimilarities between buildings based on features of their culturable communities. Blocks mark clusters with significant support (P < 0.01), based on 104 multiscale bootstrap resamples (45) of normalized feature values. The only cluster with significant support that consisted of more than three buildings is marked by a thick blue block and a colored star. Ashkaan K. Fahimipour et al. mSystems 2018; doi:10.1128/mSystems.00200-18