Relationships between annual antibiotic purchase rates and progression of microalbuminuria in patients with type 1 diabetes. Relationships between annual.

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Presentation transcript:

Relationships between annual antibiotic purchase rates and progression of microalbuminuria in patients with type 1 diabetes. Relationships between annual antibiotic purchase rates and progression of microalbuminuria in patients with type 1 diabetes. Annual number of antibiotic purchases in patients with type 1 diabetes and incident microalbuminuria (progressors, n=219; closed squares), and their age, sex, and diabetes duration (±2 years) matched controls with type 1 diabetes that have retained a normal albumin excretion rate during the whole follow-up period (non-progressors, n=874; open squares). The first year of incident microalbuminuria is shown as year 0. Controls were matched for sex, age, and diabetes duration (±2 years). Values are expressed as means with 95% CIs, and were adjusted for sex, HbA1c, and diabetes duration. A dashed horizontal line indicates the level of significance between years −4 and 0 in the incident microalbuminuria group. p Values (#p<0.05; *p<0.01;**p<0.001) apply to the differences in annual antibiotic purchase rates between progressors and non-progressors. Johan R Simonsen et al. BMJ Open Diab Res Care 2015;3:e000067 ©2015 by American Diabetes Association