Volume 63, Issue 4, Pages (April 2003)

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Volume 63, Issue 4, Pages 1211-1219 (April 2003) Association of an IL-1A 3′UTR polymorphism with end-stage renal disease and IL-1α expression Jeannette T. Bensen, Carl D. Langefeld, Liwu Li, Charles E. McCall, Susan L. Cousart, Bonnie N. Dryman, Barry I. Freedman, Donald W. Bowden Kidney International Volume 63, Issue 4, Pages 1211-1219 (April 2003) DOI: 10.1046/j.1523-1755.2003.00856.x Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 1 Genotypes corresponding to the seven single-strand conformational polymorphism (SSCP) patterns observed. Haplotypes confirmed by DNA sequencing. Kidney International 2003 63, 1211-1219DOI: (10.1046/j.1523-1755.2003.00856.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 2 Interleukin-1 alpha (IL-1A) gene (accession no. X03833) structure and 3′ untranslated region (UTR) AU-rich sequence containing polymorphisms. The two SNPs (positions 11409 and 11423), one 4 nt insertion/deletion (I/D) (position 11419..11422) polymorphism and the 6 AU-rich elements (AREs) within the genomic DNA sequence are indicated by bold type and underline. Genomic sequence is truncated at 11643 to correspond with the end of the primary transcript. Kidney International 2003 63, 1211-1219DOI: (10.1046/j.1523-1755.2003.00856.x) Copyright © 2003 International Society of Nephrology Terms and Conditions