Using Fludarabine to Reduce Exposure to Alkylating Agents in Children with Sickle Cell Disease Receiving Busulfan, Cyclophosphamide, and Antithymocyte.

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Presentation transcript:

Using Fludarabine to Reduce Exposure to Alkylating Agents in Children with Sickle Cell Disease Receiving Busulfan, Cyclophosphamide, and Antithymocyte Globulin Transplant Conditioning: Results of a Dose De-Escalation Trial  John T. Horan, Ann Haight, Jacqueline Lagerlof Dioguardi, Clark Brown, Audrey Grizzle, Chiani Shelman, Julie Kanter, Greg Hale, Michael Nieder, Melody Benton, Kimberly A. Kasow, Allistair Abraham, Kuang-Yueh Chiang  Biology of Blood and Marrow Transplantation  Volume 21, Issue 5, Pages 900-905 (May 2015) DOI: 10.1016/j.bbmt.2015.01.015 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) Changes in CD3+ peripheral blood chimerism level over time. (B) Changes in CD33+ peripheral blood chimerism level over time. Biology of Blood and Marrow Transplantation 2015 21, 900-905DOI: (10.1016/j.bbmt.2015.01.015) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions