Correlation of Polyp Number and Family History of Colon Cancer With Germline MYH Mutations  Won–Seok Jo, Prathap Bandipalliam, Kristen M. Shannon, Kristin B. Niendorf, Gayun Chan–Smutko, Chin Hur, Sapna Syngal, Daniel C. Chung  Clinical Gastroenterology and Hepatology  Volume 3, Issue 10, Pages 1022-1028 (October 2005) DOI: 10.1016/S1542-3565(05)00411-8 Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 1 Gel electrophoresis of exon 13 polymerase chain reaction products from selected patients after digestion with Bgl II restriction enzyme. The G382D mutation introduces a Bgl II restriction site not present in the wild-type sequence. Patient 214 has a G382D mutation. Clinical Gastroenterology and Hepatology 2005 3, 1022-1028DOI: (10.1016/S1542-3565(05)00411-8) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 2 DNA sequence chromatogram showing a Y165C homozygous mutation in patient 642. There is 1 peak corresponding to the presence of an adenine to guanine missense substitution in both alleles. Clinical Gastroenterology and Hepatology 2005 3, 1022-1028DOI: (10.1016/S1542-3565(05)00411-8) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 3 DNA sequence chromatogram showing a G382D heterozygous mutation in patient 273. In codon 382 there are 2 peaks corresponding to an adenine missense mutation in 1 allele and to a wild-type guanine in the second allele. Clinical Gastroenterology and Hepatology 2005 3, 1022-1028DOI: (10.1016/S1542-3565(05)00411-8) Copyright © 2005 American Gastroenterological Association Terms and Conditions