Confocal images of 3-month-old wild-type mouse and human retinas.

Slides:



Advertisements
Similar presentations
From: Deficiency of SHP-1 Protein-Tyrosine Phosphatase in “Viable Motheaten” Mice Results in Retinal Degeneration Invest. Ophthalmol. Vis. Sci ;47(3):
Advertisements

From: Role of Caveolin-1 for Blocking the Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy Invest. Ophthalmol. Vis. Sci ;58(1):
From: Wnt/β-Catenin Signaling Mediates Regeneration of Retinal Pigment Epithelium After Laser Photocoagulation in Mouse Eye Invest. Ophthalmol. Vis. Sci..
From: Canonical/β-Catenin Wnt Pathway Activation Improves Retinal Pigmented Epithelium Derivation From Human Embryonic Stem Cells Invest. Ophthalmol. Vis.
Rap1 regulates the accumulation of AJ material during ZA morphogenesis
Figure S1 a b c d DAPI Lgr β-catenin Merge
Altered cell migration factors and increased intestinal tumorigenesis in APC1638N/+ mice. Altered cell migration factors and increased intestinal tumorigenesis.
Heavy-ion radiation decreases expression of key cellular tight junction proteins and alters microtubule dynamics in mouse intestine. Heavy-ion radiation.
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
Scanning electron microscopy analysis of EGK-I to -V chick embryos.
Figure 2 Optical coherence tomography of the human retina A) Detailed retinal segmentation sample on spectral-domain optical coherence tomography (OCT)
The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications  Elisabetta Dejana, Elisabeth Tournier-Lasserve,
CCL21 localizes to T cell zone FRCs in young and aged spleens.
Fig. 3 hESC-RPE cell sheet transplantation and validation of the surgical method. hESC-RPE cell sheet transplantation and validation of the surgical method.
Detection and tracking of individual SNAP-tagged proteins on the surface of living cells. Detection and tracking of individual SNAP-tagged proteins on.
Orientation defects in stereociliary hair bundles with uncoupling from kinocilium and basal body position of hair cells in the organ of Corti of neonatal.
Fig. 6 Photoreceptor cell survival in the RCS rat retina after transplantation with hESC-RPE cell sheets. Photoreceptor cell survival in the RCS rat retina.
Differential secretion profiles of C. elegans TTR models.
Numerical analysis of cell morphology of tapetal cells in wild type.
Occurrence of prominin-1-containing particles in the ventricular fluid of the embryonic mouse brain. Occurrence of prominin-1-containing particles in the.
Generation of Crb1-/- mice and confocal images of mouse retinas.
Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.
Aberrant development of the anterior segment in AP-2β NCC KO mutants.
Localisation of epithelial markers in mMEC cultures.
Fig. 1. Prestin in mouse outer hair cells is localized along the lateral wall of the cell along with β-catenin and Na/K ATPase.Shown are cartoons of the.
Embryonic corneal defects in E18.5 AP-2β NCC KO mutant embryos.
Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.
Colocalization of the palmitoylation-deficient mutants of claudin-14 with the lysosomal membrane protein LAMP-2. Colocalization of the palmitoylation-deficient.
Fig. 1. Mitochondrial internalization in cardiomyocytes.
Establishment of intercellular adhesion in homozygous, heterozygous andβ -catenin-null mutant keratinocytes after incubation in medium containing 1.2 mM.
Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.
PfSec13 does not co-localize with P. falciparum heterochromatin.
Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice. Secondary storage of GM2 ganglioside and cholesterol in Fuca1-deficient mice.
Fig. 1. Ovarian cancer spheroids can bud from a monolayer
Apical localization of PKA fusion constructs in infected and fully differentiated human airway epithelial cells. Apical localization of PKA fusion constructs.
Fig. 8. Lhx1-RNAi perturbs NR formation
Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.
High-affinity binding to the hypervariable region of the β1 I-like domain controls signaling to fibronectin fibrillogenesis. High-affinity binding to the.
ArfGAP1 expression alters GBF1 recruitment to Golgi membranes.
Transbilayer distribution of cholesterol in the plasma membrane is defective in staurosporine-treated cells. Transbilayer distribution of cholesterol in.
Colocalisation and influence on migration.
Ezrin in its open, activated conformation binds and colocalizes with MISP at the cell cortex. Ezrin in its open, activated conformation binds and colocalizes.
Characterization of anti-N-mPres.
Cathepsin D in wild-type and Nuc1 RPE
Normal mammary morphogenesis is accomplished by a stratified epithelium. Normal mammary morphogenesis is accomplished by a stratified epithelium. (A) Carmine-Red-stained.
Prophase nuclear movements in wild-type, rec8 and rec7 mutant cells.
(A) Diagram illustrating axes of mitoses at different stages of follicle development and in different layers of the GCs. Thicker lines mark predominant.
Cdc2 expression in cultured Schwann cells.
IGF1R is present in endometrial luminal epithelium at the receptive phase. IGF1R is present in endometrial luminal epithelium at the receptive phase. Endometrial.
E4-ORF1 disrupts proper TJ localization of ZO-1 and ZO-2 in MDCK cells
Global cell proliferation replenishes epidermal cells.
CENP-F staining in prometaphase and metaphase spermatocytes from B6 and Rb/+ mice. CENP-F staining in prometaphase and metaphase spermatocytes from B6.
Proliferation on soft matrices is decoupled from myosin light chain phosphorylation, cell tractions, and focal adhesions. Proliferation on soft matrices.
Fig. 1. Rnd2 and Rnd3 induce stress fibres whereas Rnd1 reduces stress fibres in endothelial cells.(A) Rnd mRNAs are expressed in HUVECs. Total RNA was.
Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated.
PtdIns(4,5)P2 dependence of TbEpsinR and TbCALM membrane targeting.
WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates TfR. WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates.
(A,B) Immunofluorescence of Cx43 (red) and smooth muscle actin (green) in cultured myometrial cells from untreated (A) and tamoxifen-treated (B) Cx43fl/fl:SM-CreERT2.
Model of the role of Vav proteins in apical maturation.
Subnuclear localization of HA-tagged EBNA1 protein.
Ezrin phenotypes in the MVID intestine.
Generation of an inducible form of FOXN1.
Fig. 1 Device structure, typical output performance, and cytocompatibility of BD-TENG. Device structure, typical output performance, and cytocompatibility.
Recruitment of epiplakin to keratin filaments and aggregates after application of various types of stress. Recruitment of epiplakin to keratin filaments.
Ca2+-mediated differentiation of primary mouse keratinocytes is independent of epiplakin. Ca2+-mediated differentiation of primary mouse keratinocytes.
Subcellular distribution of Mst4 and aPKCι in in vivo enterocytes.
Fig. 1. DEL-1 is expressed by human and mouse osteoclasts.
Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface structures. Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface.
Specificity of the WDR81 antibody for the antigen.
Fig. 5 C9orf72 knockdown disrupts autophagy induction.
Presentation transcript:

Confocal images of 3-month-old wild-type mouse and human retinas. Confocal images of 3-month-old wild-type mouse and human retinas. These images are high power insets of the OLM. (A) Crb1 is confined to the SAR, whereas β-catenin localized more basally at the AJ. (B) Crb1 localized at the basal part of the F-actin localization in the PRC inner segments. (C) Mpp4, (D) Pals1, (E) Mupp1 and (F) Patj localized at the SAR, compared to the location of β-catenin at the AJ. (G) aPKC co-localized with Crb1 to the SAR. (H-I) Crb2 and Crb3 localized to the SAR. A similar staining was detected in Crb1-/- retina. (J) CD44 localized in the MGC apical villi, but did not co-localize with Crb1 in the SAR. Par6, moesin or ZO-3 were not detected in the OLM (data not shown). Claudin-1 to -5 and occludin were not detected in the retina, but claudin-2 and occludin were detected in the retinal pigment epithelium (RPE). (K) CRB1 localized at the SAR of the human retina, apical to β-catenin in the AJ. (L) MUPP1 localized at the SAR of the human retina. (M) Schematic diagram of the localization for the different proteins at the SAR or AJ. Scale bar: 2.5 μm. Serge A. van de Pavert et al. J Cell Sci 2004;117:4169-4177 © The Company of Biologists Limited 2004