Volume 124, Issue 5, Pages (May 2003)

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Volume 124, Issue 5, Pages 1311-1314 (May 2003) Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability Pierre Laurent-puig, Olivier Plomteux, Olivier Bluteau, Franck Zinzindohoué, Emmanuelle Jeannot, Karin Dahan, Alex Kartheuser, Caroline Chapusot, Paul-henri Cugnenc, Jessica Zucman-rossi Gastroenterology Volume 124, Issue 5, Pages 1311-1314 (May 2003) DOI: 10.1016/S0016-5085(03)00268-3

Figure 1 Exon 4 sequence electrophoregram. (A) Forward; (B) reverse. 106T nonmutated sequence showing polymorphism G → C at nucleotide 864, codon 288; 2T showing a deletion of one C at nucleotide 872 in (C)9 allele. 8T showing ins C at nucleotide 872 in (C)8 allele; 121T showing a deletion of one C at nucleotide 872 in (C)8 allele. Gastroenterology 2003 124, 1311-1314DOI: (10.1016/S0016-5085(03)00268-3)

Figure 2 Frequency of HNF1 864 G → C genotype in exon 4 according to tumor phenotype MSI-H or loss of heterozygosity. Gastroenterology 2003 124, 1311-1314DOI: (10.1016/S0016-5085(03)00268-3)