Web-based Binational Student Presentations Joint Oxford & Toronto Student Symposium for MSc in Musculoskeletal Sciences Web-based Binational Student Presentations 24th-25th June 2019

Institute Leads Toronto Leads: Oxford Leads: Associate Professor Stephanie Dakin Professor Alan Silman Lydia Underdown Toronto Leads: Professor Gillian Hawker Assistant Professor Amir Koshbin Assistant Professor Heather Baltzer Dr Bheeshma Ravi, Assistant Professor Lihi Eder

Educational Objectives Vehicle to enhance and broaden MSc Musculoskeletal students experiences from their respective taught course contents Connecting students with University Toronto and University Oxford Faculty, providing a platform to enhance future career opportunities / choices

Symposium Outcomes Bring together early stage clinician and basic scientist investigators: Foster collaborative international working within the MSK sciences Integrate studies of disease mechanism, therapeutic discovery and implementation of treatment strategies and clinical outcome Encapsulate a bench to bedside approach to the MSK sciences

How will the Symposium be run? Pre-symposium activities Students from both institutes sign up to one of a number of choices of a pre-defined research topics with a combined clinical / scientific research theme Topics will be allocated based on the student preferences and assigned in February 2019 Each group will have 2-4 students with 1 Faculty member as a facilitator Faculty member from either institution

Suggested research topics 1 Orthopaedics & Rheumatology Development of disease modifying drugs to treat OA New and emerging therapies for the management of seronegative RA Management of delayed fracture healing The future landscape for metal on metal hip implants Blood markers for OA and inflammatory arthropathies Markers for peri-prosthetic joint infection How has the introduction of DMARDs influenced joint-related surgeries for inflammatory arthritis? Topics span the musculoskeletal sciences, encompassing orthopaedics, trauma and rheumatology

Suggested research topics 2 Orthopaedics & Rheumatology Inpatient vs. outpatient total joint arthroplasty  Myoelectric vs. conventional prostheses: evidence for outcome measures in upper extremity amputees Cardio-metabolic diseases in rheumatic diseases Personalized approach for selecting medications in rheumatic diseases Pre-clinical phases of rheumatic diseases Imaging as  point-of-care in rheumatology Topics span the musculoskeletal sciences, encompassing orthopaedics, trauma and rheumatology

Suggested research topics 3 Regenerative Medicine Potential cell-based therapies to treat degenerative disc disease Stem cells in OA Smart biomaterials to enhance tissue repair Trials Improving the quality of surgical trials Placebo controlled trials of orthopaedic surgery Placebo controlled trials for knee arthroscopy

Suggested research topics 4 Pain Novel pain management approaches to combat chronic back pain Nerve conduits vs. allografts vs. autografts for nerve defects Cannabinoids for post-operative pain management Treatment modalities for Complex Regional Pain Syndrome Treatment for delayed/chronic nerve injuries

How will the Symposium be run? Pre-symposium activities Each group needs to: Come to a consensus on the problem area (research topic) Generate objectives for a research project Describe how the research could be conducted Please remember: You will not be formally assessed on your performance The process will build upon your course learning and should be seen as an opportunity to broaden your knowledge

How will the Symposium be run? Pre-symposium activities Each group will have ~3 scheduled skype calls plus time for pre-reading between Feb-June 2019 One assigned facilitator (Faculty member) will support each group after students signed up for research themes Facilitator mentors students, discusses progress via skype 2-3 times Facilitators briefed upon presentation format

Research Symposium Students present their deliberations at the Symposium in June 2019 via webinar A prize will be awarded for the best presentation and responses to questions

Symposium Timing The symposium will run over 2 afternoons of the Oxford MSc June residential week (13:00-18:00 UK Summer Time and 08:00-13:00 EST) on 24th-25th June 2019 Symposium run via video link Series of 20 minute presentations where each student participates Each presentation will be followed by a 10 min Q&A session from both students and Faculty at each Institute.

What you will need to do, once topics are assigned: We expect students to: Establish contact with your group Plan & implement strategy for dividing tasks and developing your presentation We expect this will entail organising Skype meetings with each other and your facilitator You will need to make time to prepare your power point presentation

Action plan: Select your research theme https://goo.gl/forms/5tVXQqLaTQUpSv3I2 Groups and facilitators assigned Establish contact with your group and facilitator Skype meetings with each other and facilitator between February and June 2019 Attend Symposium on 24th and 25th June 2019

Joint MSc Symposium Information Resources Website showing list of research themes, template for presentations and list of assigned facilitators:  https://weblearn.ox.ac.uk/portal/site/:medsci:department:ndorms:ox-toro-symp?panel=Main   Link to sign up to research theme: https://goo.gl/forms/5tVXQqLaTQUpSv3I2 Who to contact for help / advice at Oxford: stephanie.dakin@ndorms.ox.ac.uk alan.silman@ndorms.ox.ac.uk, lydia.underdown@ndorms.ox.ac.uk Who to contact for help / advice at Toronto: Heather.Baltzer@uhn.ca KHOSHBINAM@smh.ca bheeshma.ravi@sunnybrook.ca

Thank you for listening Any questions?