COUNTERPOINT: Does Interstitial Pneumonia With Autoimmune Features Represent a Distinct Class of Patients With Idiopathic Interstitial Pneumonia? No

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Presentation transcript:

COUNTERPOINT: Does Interstitial Pneumonia With Autoimmune Features Represent a Distinct Class of Patients With Idiopathic Interstitial Pneumonia? No Justin M. Oldham, MD, Sonye K. Danoff, MD, PhD, FCCP CHEST Volume 155, Issue 2, Pages 260-263 (February 2019) DOI: 10.1016/j.chest.2018.08.1073 Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 1 Kaplan–Meier survival curves of IPAF, IPF, and CTD-ILD cohorts. A, Overall, the IPAF cohort survival was significantly worse than the CTD-ILD cohort (P < .001) and marginally better than the IPF cohort (P = .07). B, After stratification of the IPAF cohort according to the presence of a UIP pattern on high-resolution CT imaging and/or surgical lung biopsy, patients with IPAF but without UIP demonstrated survival similar to those with CTD-ILD (P = .45), whereas those with UIP exhibited survival similar to those with IPF (P = .51). CTD-ILD = connective tissue disease-associated interstitial lung disease; IPAF = interstitial pneumonia with autoimmune features; IPF = idiopathic pulmonary fibrosis; UIP = usual interstitial pneumonia. (Reproduced with permission from the ©ERS 2018. European Respiratory Journal Jun 2016;47(6):1767-1775; https://doi.org.10.1183/13993003.01565-2015.13) CHEST 2019 155, 260-263DOI: (10.1016/j.chest.2018.08.1073) Copyright © 2018 American College of Chest Physicians Terms and Conditions