Metastatic Carcinoma of the Breast Resembling Early Gastric Carcinoma

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Metastatic Carcinoma of the Breast Resembling Early Gastric Carcinoma Manuel Pera, MD, PhD, Emilio Riera, MD, Rafael Lopez, MD, Nuria Viñolas, MD, PhD, Cleofe Romagosa, MD, Rosa Miquel, MD, PhD Mayo Clinic Proceedings Volume 76, Issue 2, Pages 205-207 (February 2001) DOI: 10.4065/76.2.205 Copyright © 2001 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 Low-power view of metastatic lobular carcinoma involving the gastric antrum wall. Note nodular infiltration of the mucosa and linitis plastica-like invasion of the submucosa and muscular layers (cytokeratin 7 immunostain, original magnification ×40). Mayo Clinic Proceedings 2001 76, 205-207DOI: (10.4065/76.2.205) Copyright © 2001 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 Small cancer cells arranged in rows, without gland formation. Occasional intracytoplasmic vacuoles were seen (arrow) (hematoxylin-eosin, original magnification ×400). Mayo Clinic Proceedings 2001 76, 205-207DOI: (10.4065/76.2.205) Copyright © 2001 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 3 Immunohistochemically, tumor cells showed diffuse nuclear positivity for progesterone receptor (peroxidase-diamino-benzidine, original magnification ×400). Mayo Clinic Proceedings 2001 76, 205-207DOI: (10.4065/76.2.205) Copyright © 2001 Mayo Foundation for Medical Education and Research Terms and Conditions