On-demand, NIR light–triggered hyperthermia termination switch for RBC microswimmers. On-demand, NIR light–triggered hyperthermia termination switch for.

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Presentation transcript:

On-demand, NIR light–triggered hyperthermia termination switch for RBC microswimmers. On-demand, NIR light–triggered hyperthermia termination switch for RBC microswimmers. (A) Schematic RBC microswimmers, loaded with a photothermal agent (ICG) coupled with BSA, generating heat upon irradiation with NIR and resulting in termination of bacteria. (B) IR thermal images of RBC microswimmers loaded inside a capillary tube before and during NIR irradiation. (C) Live/dead staining of bacteria in RBC microswimmer samples before (i) and after (ii) NIR irradiation, respectively. Scale bars, 5 μm. (D and E) Quantitative measurements of (D) number of intact RBCs and (E) percent viable bacteria before and after NIR-activated hyperthermia termination, respectively. Error bars represent the SD. Yunus Alapan et al. Sci. Robotics 2018;3:eaar4423 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works